Compile Data Set for Download or QSAR
Report error Found 33 of ki data for polymerid = 820,50004197
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541448(CHEMBL4633785)
Affinity DataKi:  1.90nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50339145(trans-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]oc...)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541449(CHEMBL4636953)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50089084(Vaborbactam | CHEMBL3317857)
Affinity DataKi:  56nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50541450(CHEMBL4640702)
Affinity DataKi:  150nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569703(CHEMBL4851703)
Affinity DataKi:  280nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569685(CHEMBL4877631)
Affinity DataKi:  730nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569681(CHEMBL4867398)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569680(CHEMBL4862416)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569686(CHEMBL4868540)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569689(CHEMBL4855728)
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569696(CHEMBL4867248)
Affinity DataKi:  1.58E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569690(CHEMBL4876416)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569699(CHEMBL4855195)
Affinity DataKi:  1.81E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569698(CHEMBL4855265)
Affinity DataKi:  1.84E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569692(CHEMBL4864504)
Affinity DataKi:  1.89E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569688(CHEMBL4848727)
Affinity DataKi:  1.93E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569697(CHEMBL4860974)
Affinity DataKi:  1.96E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569687(CHEMBL4862171)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569691(CHEMBL4866009)
Affinity DataKi:  2.36E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569684(CHEMBL4865343)
Affinity DataKi:  2.41E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569682(CHEMBL4849131)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569683(CHEMBL4849406)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569679(CHEMBL4855927)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569702(CHEMBL4864325)
Affinity DataKi:  3.69E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569704(CHEMBL4848912)
Affinity DataKi:  3.89E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569694(CHEMBL4876790)
Affinity DataKi:  3.94E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569705(CHEMBL4853896)
Affinity DataKi:  4.15E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569695(CHEMBL4875502)
Affinity DataKi:  5.23E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569701(CHEMBL4872507)
Affinity DataKi:  5.66E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569693(CHEMBL4854293)
Affinity DataKi:  6.04E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50569700(CHEMBL4872541)
Affinity DataKi:  6.49E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Qpex Biopharma

Curated by ChEMBL
LigandPNGBDBM50619648(CHEMBL2031559)
Affinity DataKi:  9.73E+4nMAssay Description:Binding affinity to Escherichia coli KPC-2 assessed as inhibition constant using nitrocefin as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed