Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2 [F130V]'
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12013(CHEMBL302715 | N-benzyl-4-sulfamoylbenzamide | 4-(...)
Affinity DataKd:  5.60nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12014(N-[(2-fluorophenyl)methyl]-4-sulfamoylbenzamide | ...)
Affinity DataKd:  2.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12015(N-[(4-fluorophenyl)methyl]-4-sulfamoylbenzamide | ...)
Affinity DataKd:  3.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12016(N-[(2,3-difluorophenyl)methyl]-4-sulfamoylbenzamid...)
Affinity DataKd:  1.60nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12017(N-[(2,4-difluorophenyl)methyl]-4-sulfamoylbenzamid...)
Affinity DataKd:  3.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12018(N-[(2,5-difluorophenyl)methyl]-4-sulfamoylbenzamid...)
Affinity DataKd:  2.20nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12019(N-[(2,6-difluorophenyl)methyl]-4-sulfamoylbenzamid...)
Affinity DataKd:  3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12020(CHEMBL66907 | 4-(AMINOSULFONYL)-N-[(2,3,4-TRIFLUOR...)
Affinity DataKd:  3.80nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12021(4-(AMINOSULFONYL)-N-[(2,4,6-TRIFLUOROPHENYL)METHYL...)
Affinity DataKd:  3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12022(4-(AMINOSULFONYL)-N-[(3,4,5-TRIFLUOROPHENYL)METHYL...)
Affinity DataKd:  3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2 [F130V](Human)
University of Pennsylvania

LigandPNGBDBM12023(N-[(2,3,4,5,6-pentafluorophenyl)methyl]-4-sulfamoy...)
Affinity DataKd:  2nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed