Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 4557
TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238166BDBM238166(US9394291, 7 | US10017502, Example 7)
Affinity DataIC50: 9.5nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 404277BDBM404277(US10017502, Example 8b)
Affinity DataIC50: 10nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 404271BDBM404271(US10017502, Example 6a)
Affinity DataIC50: 13nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238161BDBM238161(US9394291, 5a | US10017502, Example 5a)
Affinity DataIC50: 16nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238167BDBM238167(US9394291, 8b | US9394291, 8a | US9394291, 8 | US1...)
Affinity DataIC50: 40nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238163BDBM238163(US9394291, 6b | US9394291, 6a | US9394291, 6 | US1...)
Affinity DataIC50: 58nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238163BDBM238163(US9394291, 6b | US9394291, 6a | US9394291, 6 | US1...)
Affinity DataIC50: 82nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 404265BDBM404265(US10017502, Example 4a)
Affinity DataIC50: 130nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238158BDBM238158(US9394291, 4 | US10017502, Example 4)
Affinity DataIC50: 180nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 404258BDBM404258(US10017502, Example 2a)
Affinity DataIC50: 230nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 404265BDBM404265(US10017502, Example 4a)
Affinity DataIC50: 240nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 404263BDBM404263(2-{(3S or 3R)-7-Fluoro-4-[(3-oxo-3,4-dihydro-2H-1,...)
Affinity DataIC50: 270nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238155BDBM238155(US9394291, 3b | US9394291, 3 | US10017502, Example...)
Affinity DataIC50: 480nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238158BDBM238158(US9394291, 4 | US10017502, Example 4)
Affinity DataIC50: 740nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238151BDBM238151(US9394291, 1 | US10017502, Example 1)
Affinity DataIC50: 1.40E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 404276BDBM404276(US10017502, Example 8a)
Affinity DataIC50: 1.60E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238152BDBM238152(US9394291, 2a | US9394291, 2 | US10017502, Example...)
Affinity DataIC50: 1.80E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 404273BDBM404273(US10017502, Example 6b)
Affinity DataIC50: 1.90E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238151BDBM238151(US9394291, 1 | US10017502, Example 1)
Affinity DataIC50: 2.90E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238162BDBM238162(US9394291, 5b | US10017502, Example 5b)
Affinity DataIC50: 4.90E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 238159BDBM238159(US9394291, 4a | US10017502, Example 4b)
Affinity DataIC50: 3.75E+4nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMineralocorticoid receptor [729-984](Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 404262BDBM404262(2-{(3S or 3R)-7-Fluoro-4-[(3-oxo-3,4-dihydro-2H-1,...)
Affinity DataIC50: 3.75E+4nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent