Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 946
TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 292004BDBM292004((E)-3-(3,5-difluoro-4-(2-((S)-3-fluoro-2-methylpro...)
Affinity DataIC50: 200nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50125052BDBM50125052(CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...)
Affinity DataIC50: 640nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50125054BDBM50125054(CHEMBL3623003 | US10130617, Example 2 | WO-2014/19...)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 289785BDBM289785((E)-3-(3,5-Difluoro-4-((1R,3R)-2-((S)-3-fluoro-2-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 299742BDBM299742((E)-3-(3-fluoro-4-(2-((S)-3-fluoro-2-methylpropyl)...)
Affinity DataIC50: 1.20E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 292005BDBM292005((E)-3-(3,5-difluoro-4-(2-(2-fluoro-2-methylpropyl)...)
Affinity DataIC50: 1.30E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 292003BDBM292003((E)-3-(4-((1R,3R)-2-((S)-3-fluoro-2-methylpropyl)-...)
Affinity DataIC50: 1.60E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 298314BDBM298314((E)-3-(4-(2-(2-fluoro-2-methylpropyl)-3,3-dimethyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 298313BDBM298313((E)-3-(4-(2-((S)-3-fluoro-2-methylpropyl)-3,3-dime...)
Affinity DataIC50: 5.00E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent