Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 1034
LigandChemical structure of BindingDB Monomer ID 304039BDBM304039(2-[2-(2-Methoxyphenyl)-1H-benzimidazol-5-yl]-5,8-d...)
Affinity DataIC50: 19.5nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304033BDBM304033(5,8-Dimethyl-2-(2-phenyl-1H-benzimidazol-5-yl)[1,2...)
Affinity DataIC50: 27nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304043BDBM304043(5,8-Dimethyl-2-(2-phenylimidazo[1,2-a]pyrimidin-7-...)
Affinity DataIC50: 35.7nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304031BDBM304031(US10138245, Example 2)
Affinity DataIC50: 37nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304030BDBM304030(5,7-Dimethyl-2-(2-phenyl-1H-benzo[d]imidazol-5-yl)...)
Affinity DataIC50: 47nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304036BDBM304036(2-[2-(4-FLuorophenyl)-1H-benzimidazol-5-yl]-5,8-di...)
Affinity DataIC50: 54nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304038BDBM304038(5,8-Dimethyl-2-[2-(pyridin-2-yl)-1H-benzimidazol-5...)
Affinity DataIC50: 63nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304037BDBM304037(5,8-Dimethyl-2-[2-(1,3-thiazol-2-yl)-1H-benz-imida...)
Affinity DataIC50: 84nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304042BDBM304042(US10138245, Example 56)
Affinity DataIC50: 96nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304035BDBM304035(2-[2-(3-Fluorophenyl)-1H-benzimidazol-5-yl]-5,8-di...)
Affinity DataIC50: 172nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304032BDBM304032(US10138245, Example 3)
Affinity DataIC50: 279nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304041BDBM304041(US10138245, Example 48B)
Affinity DataIC50: 413nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304040BDBM304040(US10138245, Example 48A)
Affinity DataIC50: 794nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 304034BDBM304034(5,7-Dimethyl-2-[3-(pyridin-4-yl)-1H-benzimidazol-5...)
Affinity DataIC50: 953nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent