Compile Data Set for Download or QSAR
Report error Found 187 Enz. Inhib. hit(s) with all data for entry = 1872
TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345281BDBM345281(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)
Affinity DataIC50: 1nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345298BDBM345298(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopentyl...)
Affinity DataIC50: 1.10nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345296BDBM345296(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclobutylm...)
Affinity DataIC50: 2.60nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345315BDBM345315(2-([1-[(2-methoxyphenyl)methyl]-5-[3-(2- methylpr...)
Affinity DataIC50: 3.10nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345287BDBM345287(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopropyl...)
Affinity DataIC50: 3.20nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345283BDBM345283(2-[[1-[(2-Bromophenyl)methyl]-5-(3- isopropoxyphe...)
Affinity DataIC50: 3.70nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345289BDBM345289(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isopropoxyph...)
Affinity DataIC50: 5.20nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345293BDBM345293(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopropox...)
Affinity DataIC50: 5.40nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345291BDBM345291(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclobutoxy...)
Affinity DataIC50: 7.60nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345320BDBM345320(2-([1-[(2-chlorophenyl)methyl]-5-(5-methoxythiophe...)
Affinity DataIC50: 7.80nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345319BDBM345319(US10202350, Example 65 | US10214492, Example 65 | ...)
Affinity DataIC50: 8nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345318BDBM345318(US10202350, Example 64 | US10214492, Example 64 | ...)
Affinity DataIC50: 8.30nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345284BDBM345284(2-[[1-[(2-Bromophenyl)methyl]-5-(3- methoxyphenyl...)
Affinity DataIC50: 8.80nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345322BDBM345322(2-([1-[(2-Chlorophenyl)methyl]-5-(3-methoxyphenyl)...)
Affinity DataIC50: 9.10nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345288BDBM345288(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (trifluorome...)
Affinity DataIC50: 9.30nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345280BDBM345280(2-[[1-[(2-Fluorophenyl)methyl]-5-(3- isobutoxyphe...)
Affinity DataIC50: 9.40nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345321BDBM345321(2-([1-(o-Chlorophenyl)methyl]-5-(m-methoxyphenyl)-...)
Affinity DataIC50: 11nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345282BDBM345282(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- ethoxyphenyl...)
Affinity DataIC50: 12nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345297BDBM345297(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (2,2,2-trifl...)
Affinity DataIC50: 13nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345314BDBM345314(US10202350, Example 60 | US10214492, Example 60 | ...)
Affinity DataIC50: 13nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345305BDBM345305(US10202350, Example 51 | US10214492, Example 51 | ...)
Affinity DataIC50: 15nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345299BDBM345299(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (tetrahydrop...)
Affinity DataIC50: 19nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345267BDBM345267(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (trifluorome...)
Affinity DataIC50: 20nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345264BDBM345264(US10202350, Example 10 | 2-[[5-(3-Chlorophenyl)-1-...)
Affinity DataIC50: 21nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345327BDBM345327(2-([1-[(2-chlorophenyl)methyl]-5-[3-[(2-methylprop...)
Affinity DataIC50: 21nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345267BDBM345267(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (trifluorome...)
Affinity DataIC50: 22nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345265BDBM345265(2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...)
Affinity DataIC50: 25nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345268BDBM345268(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...)
Affinity DataIC50: 26nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345268BDBM345268(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...)
Affinity DataIC50: 30nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345278BDBM345278(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- thienyl)pyra...)
Affinity DataIC50: 30nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345264BDBM345264(US10202350, Example 10 | 2-[[5-(3-Chlorophenyl)-1-...)
Affinity DataIC50: 33nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345316BDBM345316(2-([1-[(3-methoxyphenyl)methyl]-5-[3-(2- methylpr...)
Affinity DataIC50: 33nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345279BDBM345279(2-[[1-[(2-Chlorophenyl)methyl]-5-(2- thienyl)pyra...)
Affinity DataIC50: 33nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345317BDBM345317(2-([1-[(4-methoxyphenyl)methyl]-5-[3-(2- methylpr...)
Affinity DataIC50: 37nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345308BDBM345308(2-({1-[(o-Chlorophenyl)methyl]-5-(m- methoxypheny...)
Affinity DataIC50: 37nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345266BDBM345266(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)
Affinity DataIC50: 38nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345268BDBM345268(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...)
Affinity DataIC50: 44nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345265BDBM345265(2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...)
Affinity DataIC50: 45nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345292BDBM345292(2-[[1-[[2-(Dimethylamino)phenyl]methyl]- 5-(3-met...)
Affinity DataIC50: 48nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345266BDBM345266(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)
Affinity DataIC50: 49nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345277BDBM345277(2-[[5-(4-Chlorophenyl)-1-(3- pyridylmethyl)pyrazo...)
Affinity DataIC50: 51nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345285BDBM345285(2-[[1-[(2-Isopropylphenyl)methyl]-5-(3- methoxyph...)
Affinity DataIC50: 53nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345258BDBM345258(US10202350, Example 4 | 2-[[1-[(2-Chlorophenyl)met...)
Affinity DataIC50: 54nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMalignant T-cell-amplified sequence 1(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345287BDBM345287(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopropyl...)
Affinity DataIC50: 54.5nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345295BDBM345295(1-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...)
Affinity DataIC50: 55nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345332BDBM345332(2-[[1-[(2-Chlorophenyl)methyl]-5-(3-hydroxyphenyl)...)
Affinity DataIC50: 59nMAssay Description:MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345257BDBM345257(US10202350, Example 3 | 2-[[5-(4-Chlorophenyl)-1-[...)
Affinity DataIC50: 60nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345259BDBM345259(US10202350, Example 5 | 2-[[5-(4-Chlorophenyl)-1-[...)
Affinity DataIC50: 63nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345258BDBM345258(US10202350, Example 4 | 2-[[1-[(2-Chlorophenyl)met...)
Affinity DataIC50: 68nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetMonocarboxylate transporter 4(Human)
Vettore

US Patent
LigandChemical structure of BindingDB Monomer ID 345262BDBM345262(US10202350, Example 8 | 2-[[1-[(2-Chlorophenyl)met...)
Affinity DataIC50: 69nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

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