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Report error Found 361 Enz. Inhib. hit(s) with all data for entry = 2819
TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381804(US10272079, Compound 161)
Affinity DataIC50:  0.631nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381783(US10272079, Compound 140)
Affinity DataIC50:  1.26nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381691(US10272079, Compound 48 | US10272079, Compound 65)
Affinity DataIC50:  1.41nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381710(US10272079, Compound 67)
Affinity DataIC50:  2nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381795(US10272079, Compound 152)
Affinity DataIC50:  2nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381762(US10272079, Compound 119)
Affinity DataIC50:  2nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381793(US10272079, Compound 150)
Affinity DataIC50:  2.51nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381826(US10272079, Compound 003)
Affinity DataIC50:  2.51nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381742(US10272079, Compound 99)
Affinity DataIC50:  2.51nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381817(US10272079, Compound 174)
Affinity DataIC50:  2.51nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381667(US10272079, Compound 24)
Affinity DataIC50:  2.63nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381758(US10272079, Compound 115)
Affinity DataIC50:  2.82nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381666(US10272079, Compound 23)
Affinity DataIC50:  2.82nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381817(US10272079, Compound 174)
Affinity DataIC50:  2.95nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381740(US10272079, Compound 97)
Affinity DataIC50:  3.16nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381778(US10272079, Compound 135)
Affinity DataIC50:  3.55nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381791(US10272079, Compound 148)
Affinity DataIC50:  3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381675(US10272079, Compound 32)
Affinity DataIC50:  3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381809(US10272079, Compound 166)
Affinity DataIC50:  3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381751(US10272079, Compound 108)
Affinity DataIC50:  3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381670(US10272079, Compound 27)
Affinity DataIC50:  3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381673(US10272079, Compound 30)
Affinity DataIC50:  3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381823(CVD-0019453 | US10272079, Compound 002 | US1027207...)
Affinity DataIC50:  3.98nMAssay Description:The ability of compounds to inhibit Rat NHE3-mediated Na+-dependent H+ antiport after application and washout was measured using a modification of th...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381741(US10272079, Compound 98)
Affinity DataIC50:  3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381810(US10272079, Compound 167)
Affinity DataIC50:  4.27nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381690(US10272079, Compound 47 | US10272079, Compound 66)
Affinity DataIC50:  4.47nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381690(US10272079, Compound 47 | US10272079, Compound 66)
Affinity DataIC50:  4.47nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381789(US10272079, Compound 146)
Affinity DataIC50:  4.47nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381648(US10272079, Compound 6)
Affinity DataIC50:  4.47nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381823(CVD-0019453 | US10272079, Compound 002 | US1027207...)
Affinity DataIC50:  5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381770(US10272079, Compound 127)
Affinity DataIC50:  5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381794(US10272079, Compound 151)
Affinity DataIC50:  5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381648(US10272079, Compound 6)
Affinity DataIC50:  5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381678(US10272079, Compound 35)
Affinity DataIC50:  5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381715(US10272079, Compound 72)
Affinity DataIC50:  5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381739(US10272079, Compound 96)
Affinity DataIC50:  5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381743(US10272079, Compound 100)
Affinity DataIC50:  5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381759(US10272079, Compound 116)
Affinity DataIC50:  5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381715(US10272079, Compound 72)
Affinity DataIC50:  5.62nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381808(US10272079, Compound 165)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381814(US10272079, Compound 171)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381815(US10272079, Compound 172)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381823(CVD-0019453 | US10272079, Compound 002 | US1027207...)
Affinity DataIC50:  6.31nMAssay Description:The ability of compounds to inhibit Rat NHE3-mediated Na+-dependent H+ antiport after application and washout was measured using a modification of th...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Rat)
Ardelyx

US Patent
LigandPNGBDBM381770(US10272079, Compound 127)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381685(US10272079, Compound 42)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381730(US10272079, Compound 87)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381760(US10272079, Compound 117)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381677(US10272079, Compound 34)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381684(US10272079, Compound 41)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetSodium/hydrogen exchanger 3(Human)
Ardelyx

US Patent
LigandPNGBDBM381707(US10272079, Compound 64)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


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