Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 11139
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 594069BDBM594069(US11584728, Compound Vatiquinone)
Affinity DataIC50: 590nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 594066BDBM594066(US11584728, Compound M | (R)-2-(3-hydroxy-3-methyl...)
Affinity DataIC50: 830nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 594030BDBM594030(US11584728, Compound E | 2-((R,6E,10E)-3-hydroxy-3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 594068BDBM594068(US11584728, Compound N | (R)-2,3,5-trimethyl-6-(12...)
Affinity DataIC50: 2.67E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 594035BDBM594035(US11584728, Compound H | (R,E)-2-(11,11-difluoro-3...)
Affinity DataIC50: 2.93E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Stealth Biotherapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 594062BDBM594062(US11584728, Compound L | 2-((S,6E,10E)-15,15-diflu...)
Affinity DataIC50: 5.76E+3nMAssay Description:Briefly, reactions were carried out in Corning 96 half-well black, flat bottom assay plates and contained final concentrations of 50 μM arachido...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent