Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 11172
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310926(US10150787, Example 9 | ((5-Bromo-2-(Carboxy)Benzo...)
Affinity DataIC50: 170nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310919(US10150787, Example 2 | 6-Bromo-5-(Difluoro(Phosph...)
Affinity DataIC50: 260nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310920(US10150787, Example 3 | ((6-Bromo-2-Carbamoylbenzo...)
Affinity DataIC50: 280nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310923(US10150787, Example 6 | ((6-Bromo-2-(Cyanomethyl)B...)
Affinity DataIC50: 370nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310918(US10150787, Example 1 | ((6-Bromo-2-(Ethoxycarbony...)
Affinity DataIC50: 450nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM50239833((3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphos...)
Affinity DataIC50: 490nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310924(US10150787, Example 7 | ((5-Bromo-2-(Ethoxycarbony...)
Affinity DataIC50: 740nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310921(US10150787, Example 4 | ((6-Bromo-2-Cyanobenzo[b]T...)
Affinity DataIC50: 1.20E+3nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310922(US10150787, Example 5 | ((6-Bromo-2-(Hydroxymethyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Royal Institution For The Advancement of Learning/Mcgill University

US Patent
LigandPNGBDBM310925(US10150787, Example 8 | ((5-Bromo-2-(Methoxycarbon...)
Affinity DataIC50: 2.90E+3nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent