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Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 11694
TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM640385(US11840523, LBC-00004 08)
Affinity DataIC50:  5.10nMAssay Description:Inhibitors (initial concentration of 10 or 60 μM, three-fold serial dilutions) were incubated with IRE1α* in cleavage buffer (20 mM HEPES, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM640388(US11840523, Compound 37 | US11840523, LBC-00004 05)
Affinity DataIC50:  5.10nMAssay Description:Inhibitors (initial concentration of 10 or 60 μM, three-fold serial dilutions) were incubated with IRE1α* in cleavage buffer (20 mM HEPES, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM640387(US11840523, LBC-00004 06)
Affinity DataIC50:  7.40nMAssay Description:Inhibitors (initial concentration of 10 or 60 μM, three-fold serial dilutions) were incubated with IRE1α* in cleavage buffer (20 mM HEPES, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM640386(US11840523, LBC-00004 07)
Affinity DataIC50:  7.5nMAssay Description:Inhibitors (initial concentration of 10 or 60 μM, three-fold serial dilutions) were incubated with IRE1α* in cleavage buffer (20 mM HEPES, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent