Compile Data Set for Download or QSAR
Report error Found 201 Enz. Inhib. hit(s) with all data for entry = 12578
TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50598700BDBM50598700(CHEMBL5194472 | US20250084084, Example 91)
Affinity DataKi:  0.0440nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711525BDBM711525(2-[3-(difluoromethoxy)-5-methoxyphenyl]-1-[(2S)-7-...)
Affinity DataKi:  0.150nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711481BDBM711481((2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-{(2S)-7-...)
Affinity DataKi:  0.180nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50598690BDBM50598690(CHEMBL5181223 | US20250084084, Example 1)
Affinity DataKi:  0.210nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711586BDBM711586(1-{(2S)-6-[5-(difluoromethyl)-1-methyl-1H-1,2,4-tr...)
Affinity DataKi:  0.220nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711478BDBM711478((2R)-2-(5-Chloro-2-methoxypyridin-4-yl)-1-[(2S)-7-...)
Affinity DataKi:  0.25nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711574BDBM711574((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)-1-[(2S)-7-...)
Affinity DataKi:  0.25nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711655BDBM711655(2-[2-(difluoromethoxy)-6-methoxypyridin-4-yl]-1-[(...)
Affinity DataKi:  0.270nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711580BDBM711580((2R)-2-(5-chloro-2-methoxypyridin-4-yl)-1-[(2S)-7-...)
Affinity DataKi:  0.280nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711479BDBM711479((2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-[7-methy...)
Affinity DataKi:  0.360nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711511BDBM711511(1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H...)
Affinity DataKi:  0.360nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50598703BDBM50598703(CHEMBL5170290 | US20250084084, Example 120)
Affinity DataKi:  0.400nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711651BDBM711651((2R)-1-{(2S)-6-[1-(difluoromethyl)-5-methyl-1H-1,2...)
Affinity DataKi:  0.410nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50598694BDBM50598694(CHEMBL5208472 | US20250084084, Example 5)
Affinity DataKi:  0.440nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711592BDBM711592(2-[2-(difluoromethyl)-6-methoxypyrimidin-4-yl]-1-[...)
Affinity DataKi:  0.440nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711555BDBM711555((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)-1-{7-methy...)
Affinity DataKi:  0.450nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50598696BDBM50598696(CHEMBL5183637 | US20250084084, Example 106)
Affinity DataKi:  0.460nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711577BDBM711577((2R)-2-(5-chloro-2-methoxypyridin-4-yl)-1-[6-(5-me...)
Affinity DataKi:  0.480nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711567BDBM711567((2R)-2-(5-chloro-2-methoxypyridin-4-yl)-1-[7-methy...)
Affinity DataKi:  0.480nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711584BDBM711584(1-{(2S)-6-[5-(difluoromethyl)-1-methyl-1H-1,2,4-tr...)
Affinity DataKi:  0.490nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711585BDBM711585((2R)-1-{(2S)-6-[5-(difluoromethyl)-1-methyl-1H-1,2...)
Affinity DataKi:  0.490nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711519BDBM711519(1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H...)
Affinity DataKi:  0.510nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711499BDBM711499(2-[5-(difluoromethyl)-2-methoxypyridin-4-yl]-1-[(2...)
Affinity DataKi:  0.520nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711504BDBM711504(2-[2-methoxy-5-(trifluoromethyl)pyridin-4-yl]-1-[(...)
Affinity DataKi:  0.530nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711466BDBM711466(2-(6-Methoxy-2-methylpyrimidin-4-yl)-1-[(2S)-7-met...)
Affinity DataKi:  0.540nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711523BDBM711523(2-[5-chloro-2-(difluoromethoxy)pyridin-4-yl]-1-[(2...)
Affinity DataKi:  0.540nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711483BDBM711483(2-(4-Fluorophenyl)-1-[7-methyl-6-(1-methyl-1H-pyra...)
Affinity DataKi:  0.600nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711476BDBM711476((2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-[(2S)-7-...)
Affinity DataKi:  0.600nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711610BDBM711610((2R)-1-[(2S)-6-(7,7-difluoro-6,7-dihydro-5H-pyrrol...)
Affinity DataKi:  0.620nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711541BDBM711541(2-[2-(difluoromethoxy)-5-fluoropyridin-4-yl]-1-[(2...)
Affinity DataKi:  0.620nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711470BDBM711470(1-[(2S)-7-Methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H...)
Affinity DataKi:  0.620nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711546BDBM711546(2-(2,6-dimethoxypyridin-4-yl)-1-[(2S)-7-methyl-6-(...)
Affinity DataKi:  0.670nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711515BDBM711515(1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H...)
Affinity DataKi:  0.680nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711617BDBM711617((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)-1-[(2S)-7-...)
Affinity DataKi:  0.720nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711572BDBM711572(1-[(2S)-7-methyl-6-(2-methyl-2H-tetrazol-5-yl)-3,4...)
Affinity DataKi:  0.730nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711575BDBM711575((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)-1-[6-(5-me...)
Affinity DataKi:  0.780nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711513BDBM711513(2-(3,4-difluorophenyl)-1-[(2S)-7-methyl-6-(pyrimid...)
Affinity DataKi:  0.810nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711663BDBM711663((2R)-1-{(2S)-6-[4-(difluoromethyl)pyrimidin-2-yl]-...)
Affinity DataKi:  0.820nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711581BDBM711581((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)-1-[(2S)-7-...)
Affinity DataKi:  0.830nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711497BDBM711497(2-(2,4-dichlorophenyl)-1-[(2S)-7-methyl-6-(pyrimid...)
Affinity DataKi:  0.900nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711601BDBM711601((2R)-1-{(2S)-6-[1-(difluoromethyl)-2-methyl-1H-imi...)
Affinity DataKi:  0.900nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711517BDBM711517(1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H...)
Affinity DataKi:  0.930nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711508BDBM711508(2-[6-(difluoromethoxy)-2-methylpyrimidin-4-yl]-1-[...)
Affinity DataKi:  0.950nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711590BDBM711590(2-[2-(difluoromethyl)-6-methoxypyrimidin-4-yl]-1-[...)
Affinity DataKi:  0.970nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50598697BDBM50598697(CHEMBL5179337 | US12187727, Example 64)
Affinity DataKi:  1nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711563BDBM711563((2R)-2-(5-chloro-2-methoxypyridin-4-yl)-1-(7-methy...)
Affinity DataKi:  1.10nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711658BDBM711658(2-[2-(difluoromethoxy)pyridin-4-yl]-1-[(2S)-7-meth...)
Affinity DataKi:  1.20nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711609BDBM711609((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)-1-[(2S)-6-...)
Affinity DataKi:  1.20nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711557BDBM711557((2R)-2-(5-chloro-2-methoxypyridin-4-yl)-1-{7-methy...)
Affinity DataKi:  1.20nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 711571BDBM711571(2-[6-(difluoromethoxy)pyridin-3-yl]-1-[(2S)-7-meth...)
Affinity DataKi:  1.20nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

Displayed 1 to 50 (of 201 total ) | Next | Last >>
Jump to: