Compile Data Set for Download or QSAR
Report error Found 1027 Enz. Inhib. hit(s) with all data for entry = 12673
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566025BDBM566025(US11414431, Compound I-593 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566023BDBM566023(US11414431, Compound I-591 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566024BDBM566024(US11414431, Compound I-592 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566021BDBM566021(US11414431, Compound I-589 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566019BDBM566019(US11414431, Compound I-587 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566020BDBM566020(US11414431, Compound I-588 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566033BDBM566033(US11414431, Compound I-601 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566029BDBM566029(US11414431, Compound I-597 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566030BDBM566030(US11414431, Compound I-598 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566009BDBM566009(US11414431, Compound I-577 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566007BDBM566007(US11414431, Compound I-575 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566008BDBM566008(US11414431, Compound I-576 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566005BDBM566005(US11414431, Compound I-573 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566006BDBM566006(US11414431, Compound I-574 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566003BDBM566003(US11414431, Compound I-571 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566017BDBM566017(US11414431, Compound I-585 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566015BDBM566015(US11414431, Compound I-583 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566016BDBM566016(US11414431, Compound I-584 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566011BDBM566011(US11414431, Compound I-579 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566012BDBM566012(US11414431, Compound I-580 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566057BDBM566057(US11414431, Compound I-625 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566055BDBM566055(US11414431, Compound I-623 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566056BDBM566056(US11414431, Compound I-624 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566053BDBM566053(US11414431, Compound I-621 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566054BDBM566054(US11414431, Compound I-622 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566051BDBM566051(US11414431, Compound I-619 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566065BDBM566065(US11414431, Compound I-633 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566066BDBM566066(US11414431, Compound I-634 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566063BDBM566063(US11414431, Compound I-631 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566061BDBM566061(US11414431, Compound I-629 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566062BDBM566062(US11414431, Compound I-630 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566059BDBM566059(US11414431, Compound I-627 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566041BDBM566041(US11414431, Compound I-609 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566042BDBM566042(US11414431, Compound I-610 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566040BDBM566040(US11414431, Compound I-608 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566038BDBM566038(US11414431, Compound I-606 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566050BDBM566050(US11414431, Compound I-618 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566047BDBM566047(US11414431, Compound I-615 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566048BDBM566048(US11414431, Compound I-616 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566045BDBM566045(US11414431, Compound I-613 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566044BDBM566044(US11414431, Compound I-612 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566089BDBM566089(US11414431, Compound I-657 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566087BDBM566087(US11414431, Compound I-655 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566088BDBM566088(US11414431, Compound I-656 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566085BDBM566085(US11414431, Compound I-653 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566086BDBM566086(US11414431, Compound I-654 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566083BDBM566083(US11414431, Compound I-651 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566084BDBM566084(US11414431, Compound I-652 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566097BDBM566097(US11414431, Compound I-665 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 566098BDBM566098(US11414431, Compound I-666 | US12221453, Compound ...)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

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