Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 13535
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801848BDBM801848(US12606540, Compound 1)
Affinity DataIC50: 0.710nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801867BDBM801867(US12606540, Compound 39)
Affinity DataIC50: 1.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801864BDBM801864(US12606540, Compound 36)
Affinity DataIC50: 1.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801858BDBM801858(US12606540, Compound 27)
Affinity DataIC50: 1.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801857BDBM801857(US12606540, Compound 26)
Affinity DataIC50: 1.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801859BDBM801859(US12606540, Compound 28)
Affinity DataIC50: 2.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801863BDBM801863(US12606540, Compound 35)
Affinity DataIC50: 2.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801850BDBM801850(US12606540, Compound 5)
Affinity DataIC50: 3.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801862BDBM801862(US12606540, Compound 32)
Affinity DataIC50: 3.90nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801849BDBM801849(US12606540, Compound 2)
Affinity DataIC50: 3.90nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801860BDBM801860(US12606540, Compound 29)
Affinity DataIC50: 4.70nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801856BDBM801856(US12606540, Compound 25)
Affinity DataIC50: 6nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801868BDBM801868(US12606540, Compound 40)
Affinity DataIC50: 7.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801861BDBM801861(US12606540, Compound 30)
Affinity DataIC50: 8nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801855BDBM801855(US12606540, Compound 24)
Affinity DataIC50: 8nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801854BDBM801854(US12606540, Compound 23)
Affinity DataIC50: 9nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801852BDBM801852(US12606540, Compound 21)
Affinity DataIC50: 9nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801851BDBM801851(US12606540, Compound 6)
Affinity DataIC50: 12.4nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801866BDBM801866(US12606540, Compound 38)
Affinity DataIC50: 26.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801865BDBM801865(US12606540, Compound 37)
Affinity DataIC50: 31.8nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801853BDBM801853(US12606540, Compound 22)
Affinity DataIC50: 121nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent