Compile Data Set for Download or QSAR
Report error Found 122 Enz. Inhib. hit(s) with all data for entry = 5844
TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97403BDBM97403(Orexin receptor antagonist 35 | US20130102619, 35)
Affinity DataKi:  1nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97397BDBM97397(Orexin receptor antagonist 7 | Orexin receptor ant...)
Affinity DataKi:  1.10nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97397BDBM97397(Orexin receptor antagonist 7 | Orexin receptor ant...)
Affinity DataKi:  1.30nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97407BDBM97407(Orexin receptor antagonist 2 | US20130102619, 2)
Affinity DataKi:  1.30nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97406BDBM97406(Orexin receptor antagonist 1 | US20130102619, 1)
Affinity DataKi:  1.60nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97400BDBM97400(Orexin receptor antagonist 32 | US20130102619, 32)
Affinity DataKi:  2.10nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97404BDBM97404(Orexin receptor antagonist 36 | US20130102619, 36)
Affinity DataKi:  2.10nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97374BDBM97374(Orexin receptor antagonist 4 | US20130102619, 4)
Affinity DataKi:  2.30nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97373BDBM97373(Orexin receptor antagonist 5 | US20130102619, 5)
Affinity DataKi:  3nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97390BDBM97390(Orexin receptor antagonist 22 | US20130102619, 22)
Affinity DataKi:  3.40nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97377BDBM97377(Orexin receptor antagonist 8 | US20130102619, 8)
Affinity DataKi:  3.5nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97402BDBM97402(Orexin receptor antagonist 34 | US20130102619, 34)
Affinity DataKi:  3.5nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97378BDBM97378(Orexin receptor antagonist 9 | US20130102619, 9)
Affinity DataKi:  3.70nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97408BDBM97408(Orexin receptor antagonist 3 | US20130102619, 3)
Affinity DataKi:  4.5nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97375BDBM97375(Orexin receptor antagonist 6 | US20130102619, 6)
Affinity DataKi:  5.5nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97379BDBM97379(Orexin receptor antagonist 10 | US20130102619, 10)
Affinity DataKi:  5.90nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97399BDBM97399(Orexin receptor antagonist 31 | US20130102619, 31)
Affinity DataKi:  5.90nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97384BDBM97384(Orexin receptor antagonist 15 | US20130102619, 15)
Affinity DataKi:  9.10nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97388BDBM97388(Orexin receptor antagonist 20 | US20130102619, 20)
Affinity DataKi:  11.5nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97406BDBM97406(Orexin receptor antagonist 1 | US20130102619, 1)
Affinity DataIC50: 12nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97397BDBM97397(Orexin receptor antagonist 7 | Orexin receptor ant...)
Affinity DataIC50: 12nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97401BDBM97401(Orexin receptor antagonist 33 | US20130102619, 33)
Affinity DataKi:  12.4nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97383BDBM97383(Orexin receptor antagonist 14 | US20130102619, 14)
Affinity DataKi:  15nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 120778BDBM120778(US8710076, F-2)
Affinity DataIC50: 15nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97385BDBM97385(Orexin receptor antagonist 17 | US20130102619, 17)
Affinity DataKi:  15nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 120778BDBM120778(US8710076, F-2)
Affinity DataIC50: 16nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97373BDBM97373(Orexin receptor antagonist 5 | US20130102619, 5)
Affinity DataIC50: 17nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97397BDBM97397(Orexin receptor antagonist 7 | Orexin receptor ant...)
Affinity DataIC50: 17nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97375BDBM97375(Orexin receptor antagonist 6 | US20130102619, 6)
Affinity DataIC50: 18nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97408BDBM97408(Orexin receptor antagonist 3 | US20130102619, 3)
Affinity DataIC50: 18nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97378BDBM97378(Orexin receptor antagonist 9 | US20130102619, 9)
Affinity DataIC50: 22nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97390BDBM97390(Orexin receptor antagonist 22 | US20130102619, 22)
Affinity DataIC50: 23nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97407BDBM97407(Orexin receptor antagonist 2 | US20130102619, 2)
Affinity DataIC50: 28nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97374BDBM97374(Orexin receptor antagonist 4 | US20130102619, 4)
Affinity DataIC50: 29nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97379BDBM97379(Orexin receptor antagonist 10 | US20130102619, 10)
Affinity DataIC50: 29nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97377BDBM97377(Orexin receptor antagonist 8 | US20130102619, 8)
Affinity DataIC50: 29nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97403BDBM97403(Orexin receptor antagonist 35 | US20130102619, 35)
Affinity DataIC50: 31nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 64581BDBM64581(US20130102619, Example 1-3)
Affinity DataIC50: 32nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97391BDBM97391(Orexin receptor antagonist 23 | US20130102619, 23)
Affinity DataKi:  35nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97399BDBM97399(Orexin receptor antagonist 31 | US20130102619, 31)
Affinity DataIC50: 38nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97400BDBM97400(Orexin receptor antagonist 32 | US20130102619, 32)
Affinity DataIC50: 44nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97404BDBM97404(Orexin receptor antagonist 36 | US20130102619, 36)
Affinity DataIC50: 47nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 64582BDBM64582(US20130102619, Example 1-4)
Affinity DataIC50: 47nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97402BDBM97402(Orexin receptor antagonist 34 | US20130102619, 34)
Affinity DataIC50: 48nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97401BDBM97401(Orexin receptor antagonist 33 | US20130102619, 33)
Affinity DataIC50: 52nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97376BDBM97376(Orexin receptor antagonist 16 | US20130102619, 16)
Affinity DataKi:  57nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97384BDBM97384(Orexin receptor antagonist 15 | US20130102619, 15)
Affinity DataIC50: 62nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97383BDBM97383(Orexin receptor antagonist 14 | US20130102619, 14)
Affinity DataIC50: 65nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Rat)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97388BDBM97388(Orexin receptor antagonist 20 | US20130102619, 20)
Affinity DataIC50: 67nMT: 2°CAssay Description:Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are grown in Iscove's modified DMEM containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 97392BDBM97392(Orexin receptor antagonist 24 | US20130102619, 24)
Affinity DataKi:  79nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

Displayed 1 to 50 (of 122 total ) | Next | Last >>
Jump to: