Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 12380
TargetReplicase polyprotein 1a(SARS-CoV)
Tencent Technology (Shenzhen)

US Patent
LigandChemical structure of BindingDB Monomer ID 699308BDBM699308(N-((3S, 14S, 17aS, 18aR, 18bS)-3-cyano-18,18-dimet...)
Affinity DataIC50: 16nMAssay Description:An objective of this experiment is to detect the in vitro inhibitory activity against Mpro of the compound of the present disclosure.Experimental mat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Tencent Technology (Shenzhen)

US Patent
LigandChemical structure of BindingDB Monomer ID 699309BDBM699309(US20240327458, Compound 8b)
Affinity DataIC50: 138nMAssay Description:An objective of this experiment is to detect the in vitro inhibitory activity against Mpro of the compound of the present disclosure.Experimental mat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Tencent Technology (Shenzhen)

US Patent
LigandChemical structure of BindingDB Monomer ID 699303BDBM699303(N-((3S, 15S, 18aS, 19aR, 19bS)-3-cyano-19,19-dimet...)
Affinity DataIC50: 254nMAssay Description:An objective of this experiment is to detect the in vitro inhibitory activity against Mpro of the compound of the present disclosure.Experimental mat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Tencent Technology (Shenzhen)

US Patent
LigandChemical structure of BindingDB Monomer ID 699306BDBM699306(N-((3S, 16S, 19aS, 20aR, 20bS)-3-cyano-20,20-dimet...)
Affinity DataIC50: 379nMAssay Description:An objective of this experiment is to detect the in vitro inhibitory activity against Mpro of the compound of the present disclosure.Experimental mat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Tencent Technology (Shenzhen)

US Patent
LigandChemical structure of BindingDB Monomer ID 699305BDBM699305(N-((3S, 15S, 18aS, 19aR, 19bS, Z)-3-cyano-19,19-di...)
Affinity DataIC50: 411nMAssay Description:An objective of this experiment is to detect the in vitro inhibitory activity against Mpro of the compound of the present disclosure.Experimental mat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
US Patent