Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 12408
LigandChemical structure of BindingDB Monomer ID 701094BDBM701094((3aS,6aR)-5-[1-methyl-6-[2- (4-phenyl-1H-imidazol-...)
Affinity DataIC50: 0.0250nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701102BDBM701102(US20240343729, Example 17)
Affinity DataIC50: 0.0320nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701097BDBM701097((3R)-3-Methyl-4-[2-[2-(1- methyl-4-phenyl-imidazol...)
Affinity DataIC50: 0.0400nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701095BDBM701095(2-[3-[2-[2-[4-[(3aS,6aR)- 1,3,3a,4,6,6a- Hexahydro...)
Affinity DataIC50: 0.0400nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701108BDBM701108(US20240343729, Example 23)
Affinity DataIC50: 0.0400nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701106BDBM701106(US20240343729, Example 21)
Affinity DataIC50: 0.0500nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700244BDBM700244(2-[[4-[1-Methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701119BDBM701119(US20240343729, Reference Example A)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701101BDBM701101(US20240343729, Example 16)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701109BDBM701109(US20240343729, Example 24)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700249BDBM700249(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700248BDBM700248(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [4-[1-...)
Affinity DataIC50: 0.100nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701088BDBM701088(US20240343729, Example 3)
Affinity DataIC50: 0.102nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701103BDBM701103(US20240343729, Example 18)
Affinity DataIC50: 0.102nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701111BDBM701111((3aR,6aS)-5-(1- (Cyclopropylmethyl)-6-((4- phenyl-...)
Affinity DataIC50: 0.102nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701110BDBM701110((3aR,6aS)-5-(1-isopPropyl- 6-((4-phenyl-1H-imidazo...)
Affinity DataIC50: 0.112nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701114BDBM701114((R)-3-Methyl-4-(9-methyl-2- ((4-phenyl-1H-imidazol...)
Affinity DataIC50: 0.120nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700257BDBM700257(N-[Dimethyl(oxo)-λ6-sulfanylidene]-2-[[4-[1-m...)
Affinity DataIC50: 0.120nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701117BDBM701117((R)-3-Methyl-4-(9-methyl-2- ((4-(pyridin-3-yl)-1H-...)
Affinity DataIC50: 0.126nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701096BDBM701096(4-[2-[2-(1-Methyl-4-phenyl- imidazol-2-yl)ethynyl]...)
Affinity DataIC50: 0.158nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700263BDBM700263(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.174nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701105BDBM701105(US20240343729, Example 20)
Affinity DataIC50: 0.295nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701112BDBM701112((3aR,6aS)-5-(1-(Oxetan-3- yl)-6-((4-phenyl-1H- imi...)
Affinity DataIC50: 0.324nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700261BDBM700261(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.372nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701104BDBM701104(US20240343729, Example 19)
Affinity DataIC50: 0.389nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701090BDBM701090(US20240343729, Example 5)
Affinity DataIC50: 0.427nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701099BDBM701099(US20240343729, Example 14)
Affinity DataIC50: 0.447nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701113BDBM701113((3aR,6aS)-5-(9-Methyl-2-((4- phenyl-1H-imidazol-2-...)
Affinity DataIC50: 0.457nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701086BDBM701086(US20240343729, Example 1)
Affinity DataIC50: 0.550nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701092BDBM701092(US20240343729, Example 7)
Affinity DataIC50: 0.603nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701107BDBM701107(US20240343729, Example 22)
Affinity DataIC50: 0.603nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701091BDBM701091(US20240343729, Example 6)
Affinity DataIC50: 0.631nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701089BDBM701089(US20240343729, Example 4)
Affinity DataIC50: 1nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701115BDBM701115((S)-3-Methyl-4-(9-methyl-2- ((4-phenyl-1H-imidazol...)
Affinity DataIC50: 1.07nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701116BDBM701116((3aR,6aS)-5-(9-Methyl-2-((4- (pyridin-3-yl)-1H-imi...)
Affinity DataIC50: 1.12nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701098BDBM701098((3S)-3-Methyl-4-[2-[2-(1- methyl-4-phenyl-imidazol...)
Affinity DataIC50: 1.20nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701100BDBM701100(US20240343729, Example 15)
Affinity DataIC50: 1.91nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701118BDBM701118((S)-3-Methyl-4-(9-methyl-2- ((4-(pyridin-3-yl)-1H-...)
Affinity DataIC50: 2.09nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701087BDBM701087(US20240343729, Example 2)
Affinity DataIC50: 2.40nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 701093BDBM701093(US20240343729, Example 8)
Affinity DataIC50: 3.55nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent