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Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 12884
Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737421BDBM737421(US20250136601, Compound I-15)
Affinity DataKi:  7nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737433BDBM737433((8aR,12aS)-11-(3-(2-methoxyphenyl)propyl)-6,7,8a,9...)
Affinity DataKi:  8nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737429BDBM737429((6bS,10aR)-8-(3-(2-methoxyphenyl)propyl)-1,2,6b,7,...)
Affinity DataKi:  11nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737416BDBM737416((6bR,10aS)-8-(3-(2-methoxy)propyl)-3-methyl-2,3,6b...)
Affinity DataKi:  13nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737409BDBM737409((6bR,10aS)-8-(2-methoxyphenyl)-3-methyl-2,3,6b,7,8...)
Affinity DataKi:  17nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737425BDBM737425((7aR,11aS)-10-(3-(2-methoxyphenyl)propyl)-5,6,7a,8...)
Affinity DataKi:  18nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737423BDBM737423((7aR,11aS)-10-(2-methoxyphenethyl)-5,6,7a,8,9,10,1...)
Affinity DataKi:  24nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737420BDBM737420(US20250136601, Compound I-14)
Affinity DataKi:  28nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737415BDBM737415(2-(2-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydr...)
Affinity DataKi:  31nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737431BDBM737431((8aR,12aS)-11-(2-methoxyphenethyl)-6,7,8a,9,10,11,...)
Affinity DataKi:  32nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737419BDBM737419(US20250136601, Compound I-13)
Affinity DataKi:  34nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737427BDBM737427((6bS,10aR)-8-(2-methoxyphenethyl)-1,2,6b,7,8,9,10,...)
Affinity DataKi:  43nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737430BDBM737430((8aS,12aR)-11-(2-methoxyphenethyl)-6,7,8a,9,10,11,...)
Affinity DataKi:  45nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737424BDBM737424(10-(3-(2-methoxyphenyl)propyl)-5,6,7a,8,9,10,11,11...)
Affinity DataKi:  57nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737422BDBM737422((7aS,11aR)-10-(2-methoxyphenethyl)-5,6,7a,8,9,10,1...)
Affinity DataKi:  65nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737410BDBM737410((6bR,10aS)-8-(3-methoxyphenyl)-3-methyl-2,3,6b,7,8...)
Affinity DataKi:  88nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737417BDBM737417(2-(3-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydr...)
Affinity DataKi:  89nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737432BDBM737432((8aS,12aR)-11-(3-(2-methoxyphenyl)propyl)-6,7,8a,9...)
Affinity DataKi:  93nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737428BDBM737428((6bR,10aS)-8-(3-(2-methoxyphenyl)propyl)-1,2,6b,7,...)
Affinity DataKi:  99nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737426BDBM737426((6bR,10aS)-8-(2-methoxyphenethyl)-1,2,6b,7,8,9,10,...)
Affinity DataKi:  107nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737411BDBM737411((6bR,10aS)-8-(4-methoxyphenyl)-3-methyl-2,3,6b,7,8...)
Affinity DataKi:  126nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737418BDBM737418(US20250136601, Compound I-12)
Affinity DataKi:  190nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737407BDBM737407((6bR,10aS)-8-(2-methoxyphenyl)-3-methyl-2,3,6b,7,8...)
Affinity DataKi:  246nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737408BDBM737408(2-(((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-...)
Affinity DataKi:  525nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737413BDBM737413((6bR,10aS)-8-(2,4-methoxyphenyl)-3-methyl-2,3,6b,7...)
Affinity DataKi:  1.58E+3nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737414BDBM737414((6bR,10aS)-8-(2,5-dimethoxy)-3-methyl-2,3,6b,7,8,9...)
Affinity DataKi:  3.06E+3nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandChemical structure of BindingDB Monomer ID 737412BDBM737412((6bR,10aS)-8-(2,3-dimethoxyphenyl)-3-methyl-2,3,6b...)
Affinity DataKi:  5.25E+3nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent