Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 13336
TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781937(US20250320234, Compound 43)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781936(US20250320234, Compound 42)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722813(US20250059213, Compound 35 | US20250320234, Compou...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781930(US20250320234, Compound 36)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781945(US20250320234, Compound 56)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781944(US20250320234, Compound 55)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781943(US20250320234, Compound 54)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781941(US20250320234, Compound 52)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781940(US20250320234, Compound 51)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781938(US20250320234, Compound 44)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781919(US20250320234, Compound 25)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781918(US20250320234, Compound 24)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781917(US20250320234, Compound 23)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781915(US20250320234, Compound 21)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781914(US20250320234, Compound 20)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781929(US20250320234, Compound 35)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781928(US20250320234, Compound 34)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722800(US20250059213, Compound 13 | US20250320234, Compou...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781926(US20250320234, Compound 32)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781925(US20250320234, Compound 31)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781905(US20250320234, Compound 11)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781904(US20250320234, Compound 10)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781903(US20250320234, Compound 9)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781901(US20250320234, Compound 7)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781900(US20250320234, Compound 6)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781899(US20250320234, Compound 5)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722826(US20250059213, Compound 50 | US20250320234, Compou...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781908(US20250320234, Compound 14)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722809(US20250059213, Compound 29 | US20250320234, Compou...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781906(US20250320234, Compound 12)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781946(US20250320234, Compound 57)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722825(US20250059213, Compound 48 | US20250320234, Compou...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781848(US20250320234, Compound 1)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781921(US20250320234, Compound 27)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781935(US20250320234, Compound 41)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781902(US20250320234, Compound 8)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781932(US20250320234, Compound 38)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781912(US20250320234, Compound 18)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM722815(US20250059213, Compound 38 | US20250320234, Compou...)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781911(US20250320234, Compound 17)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781910(US20250320234, Compound 16)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781909(US20250320234, Compound 15)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781924(US20250320234, Compound 30)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781939(US20250320234, Compound 45)
Affinity DataIC50: 275nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781920(US20250320234, Compound 26)
Affinity DataIC50: 2.75E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781934(US20250320234, Compound 40)
Affinity DataIC50: 2.75E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781933(US20250320234, Compound 39)
Affinity DataIC50: 2.75E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781913(US20250320234, Compound 19)
Affinity DataIC50: 2.75E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781942(US20250320234, Compound 53)
Affinity DataIC50: 2.75E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781923(US20250320234, Compound 29)
Affinity DataIC50: 2.75E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details US Patent

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