Compile Data Set for Download or QSAR
Report error Found 84 Enz. Inhib. hit(s) with all data for entry = 13548
LigandChemical structure of BindingDB Monomer ID 802617BDBM802617((S)-1-(5-((1-methyl-1H-benzo[d] imidazol-6-yl)thio...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802618BDBM802618((S)-5-((5-(4'-amino-4'H,6'H- spiro[piperidine-4,5'...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802619BDBM802619((S)-1-(5-((8-(trifluoromethyl) quinolin-5-yl)thio)...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802620BDBM802620((S)-1-(5-((8-fluoroquinolin-5-yl) thio)pyrazin-2-y...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802621BDBM802621((S)-1-(5-((3-cyclopropyl-2- fluorophenyl)thio)pyra...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802622BDBM802622((S)-1-(5-((8-chloroquinolin-5- yl)thio)pyrazin-2-y...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802623BDBM802623((S)-1-(5-((2-(difluoromethyl)-3- fluorophenyl)thio...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802624BDBM802624((S)-1-(5-((2-(difluoromethyl) phenyl)thio)pyrazin-...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802609BDBM802609((S)-1-(5-((3-fluoro-2-methylphenyl) thio)pyrazin-2...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802610BDBM802610((S)-1-(5-((3-(difluoromethyl)-2- fluorophenyl)thio...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802611BDBM802611((S)-1-(5-((4-(difluoromethyl)-2- fluorophenyl)thio...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802612BDBM802612((S)-1-(5-((2-fluoro-3-methoxyphenyl) thio)pyrazin-...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802613BDBM802613((S)-1-(5-(quinolin-5-ylthio) pyrazin-2-yl)-4'H,6'H...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802614BDBM802614((S)-1-(5-((5-chloro-4-methylpyridin- 3-yl)thio)pyr...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802615BDBM802615((S)-1-(5-((2-chlorophenyl)thio) pyrazin-2-yl)-4'H,...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802616BDBM802616((S)-1-(5-((2-fluoro-4-methoxyphenyl) thio)pyrazin-...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802633BDBM802633((S)-1-(5-((2-fluoro-3-(1H-pyrazol- 1-yl)phenyl)thi...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802634BDBM802634((S)-1-(5-((2-chloro-3-(2- (difluoromethyl)-1H-imid...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802635BDBM802635((S)-1-(5-((7-fluoro-2-methyl-2H- indazol-6-yl)thio...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802636BDBM802636((S)-1-(5-((4-chloro-2-methyl-2H- indazol-5-yl)thio...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802625BDBM802625((S)-1-(5-((8-(difluoromethoxy) quinolin-5-yl)thio)...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802626BDBM802626((S)-1-(5-((5-(difluoromethyl)-2- fluorophenyl)thio...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802627BDBM802627((S)-1-(5-((2,6-difluorophenyl)thio) pyrazin-2-yl)-...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802628BDBM802628((S)-4-((5-(4'-amino-4'H,6'H- spiro[piperidine-4,5'...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802629BDBM802629((S)-1-(5-((2,4,5-trifluorophenyl)thio) pyrazin-2-y...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802630BDBM802630((S)-1-(5-(2-fluorophenoxy) pyrazin-2-yl)-4'H,6'H- ...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802631BDBM802631((S)-1-(5-(4-chloro-2-fluorophenoxy) pyrazin-2-yl)-...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802632BDBM802632((S)-1-(5-((3-fluoro-2-(1H-pyrazol- 1-yl)phenyl)thi...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802310BDBM802310((S)-6-(4'-amino-3'-fluoro-4'H,6'H- spiro[piperidin...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802312BDBM802312((S)-1-(5-(2,3-dichlorophenoxy) pyrazin-2-yl)-4'H,6...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802313BDBM802313((S)-6-(4'-amino-4'H,6'H-spiro [piperidine-4,5'-pyr...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802318BDBM802318((S)-1-(5-((3-fluoro-2-methylpyridin- 4-yl)thio)-6-...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802366BDBM802366((S)-1-(5-((2,3-dichlorophenyl)thio)- 6-methylpyraz...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802369BDBM802369((S)-1-(5-(4-fluorophenoxy) pyrazin-2-yl)-4'H,6'H- ...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802380BDBM802380((S)-1-(6-(2,3-difluorophenyl) pyrido[2,3-b]pyrazin...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802500BDBM802500((S)-1-(5-((2,3-dichlorophenyl)thio)- 3-methylpyraz...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802519BDBM802519((S)-1-(5-((4-(trifluoromethoxy) phenyl)thio)pyrazi...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802526BDBM802526((S)-1-(5-((4-(trifluoromethyl) phenyl)thio)pyrazin...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802531BDBM802531((S)-1-(5-((3-chlorophenyl)thio) pyrazin-2-yl)-4'H,...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802545BDBM802545((S)-1-(5-((2-fluorophenyl)thio) pyrazin-2-yl)-4'H,...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802567BDBM802567((S)-1-(5-((2,4-dichlorophenyl)thio) pyrazin-2-yl)-...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802570BDBM802570((S)-1-(5-((3,4-dichlorophenyl)thio) pyrazin-2-yl)-...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802571BDBM802571((S)-1-(5-(phenylthio)pyrazin-2-yl)- 4'H,6'H-spiro[...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802384BDBM802384((S)-1-(6-(2,3-dichlorophenyl) pyrido[2,3-b]pyrazin...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802393BDBM802393((S)-1-(5-((2-chloro-3-(1H-pyrazol- 1-yl)phenyl)thi...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802441BDBM802441((S)-1-(3-(2-fluoro-3-methylphenyl) imidazo[1,5-a]p...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802453BDBM802453((S)-1-(5-((4-fluorophenyl)thio) pyrazin-2-yl)-4'H,...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802456BDBM802456((S)-1-(3-(2-chloro-3-fluorophenyl) imidazo[1,5-a]p...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802479BDBM802479((S)-1-(3-(3-chloro-2-methylphenyl) imidazo[1,5-a]p...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 802585BDBM802585((S)-1-(5-((3-chloro-2-methylphenyl) thio)pyrazin-2...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

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