Compile Data Set for Download or QSAR
Report error Found 135 Enz. Inhib. hit(s) with all data for entry = 6075
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107475BDBM107475(US8592410, 15)
Affinity DataIC50: 0.490nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50353390BDBM50353390(US8575157, 193 | US8598163, 63 | CHEMBL1829768 | U...)
Affinity DataIC50: 0.510nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107485BDBM107485(US8598163, 69 | US8575157, 199 | US8592410, Compar...)
Affinity DataIC50: 0.550nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50353392BDBM50353392(US8598163, 67 | US8575157, 197 | CHEMBL1829761 | U...)
Affinity DataIC50: 0.550nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50353405BDBM50353405(CHEMBL1829759 | US8575157, 196 | US8592410, 93 | U...)
Affinity DataIC50: 0.720nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50353386BDBM50353386(US8592410, 88 | CHEMBL1829763 | US8598163, 61 | US...)
Affinity DataIC50: 0.75nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107487BDBM107487(US8575157, 201 | US8598163, 71 | US8592410, Compar...)
Affinity DataIC50: 0.760nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107481BDBM107481(US8575157, 189 | US8598163, 59 | US8592410, Compar...)
Affinity DataIC50: 0.770nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107489BDBM107489(US8575157, 203 | US8598163, 73 | US8592410, Compar...)
Affinity DataIC50: 0.790nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107479BDBM107479(US8592410, 19)
Affinity DataIC50: 0.860nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107492BDBM107492(US8592410, 5)
Affinity DataIC50: 0.910nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107469BDBM107469(US8592410, 4)
Affinity DataIC50: 0.930nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50353387BDBM50353387(CHEMBL1829777 | US8598163, 65 | US8575157, 195 | U...)
Affinity DataIC50: 0.990nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107486BDBM107486(US8575157, 200 | US8598163, 70 | US8592410, Compar...)
Affinity DataIC50: 1.08nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107480BDBM107480(US8592410, 20)
Affinity DataIC50: 1.08nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107476BDBM107476(US8592410, 16)
Affinity DataIC50: 1.14nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107477BDBM107477(US8592410, 17)
Affinity DataIC50: 1.25nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107488BDBM107488(US8575157, 202 | US8598163, 72 | US8592410, Compar...)
Affinity DataIC50: 1.30nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107473BDBM107473(US8592410, 13)
Affinity DataIC50: 1.39nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107483BDBM107483(US8575157, 192 | US8598163, 62 | US8592410, Compar...)
Affinity DataIC50: 1.44nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107484BDBM107484(US8598163, 64 | US8575157, 194 | US8592410, Compar...)
Affinity DataIC50: 1.48nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107474BDBM107474(US8592410, 14)
Affinity DataIC50: 1.52nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107496BDBM107496(US8592410, 12)
Affinity DataIC50: 1.78nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50353395BDBM50353395(US8598163, 68 | CHEMBL1829782 | US8592410, 95 | US...)
Affinity DataIC50: 1.79nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107482BDBM107482(US8598163, 60 | US8575157, 190 | US8592410, Compar...)
Affinity DataIC50: 1.80nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107471BDBM107471(US8592410, 10)
Affinity DataIC50: 1.90nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107469BDBM107469(US8592410, 4)
Affinity DataIC50: 1.95nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107492BDBM107492(US8592410, 5)
Affinity DataIC50: 2.32nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107475BDBM107475(US8592410, 15)
Affinity DataIC50: 2.70nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107480BDBM107480(US8592410, 20)
Affinity DataIC50: 3.26nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107476BDBM107476(US8592410, 16)
Affinity DataIC50: 3.83nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107474BDBM107474(US8592410, 14)
Affinity DataIC50: 4.05nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107479BDBM107479(US8592410, 19)
Affinity DataIC50: 4.97nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107470BDBM107470(US8592410, 9)
Affinity DataIC50: 5.02nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107477BDBM107477(US8592410, 17)
Affinity DataIC50: 6.08nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107496BDBM107496(US8592410, 12)
Affinity DataIC50: 6.10nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107491BDBM107491(US8592410, 2)
Affinity DataIC50: 6.16nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107487BDBM107487(US8575157, 201 | US8598163, 71 | US8592410, Compar...)
Affinity DataIC50: 6.32nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107494BDBM107494(US8592410, 7)
Affinity DataIC50: 7.20nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107471BDBM107471(US8592410, 10)
Affinity DataIC50: 8.04nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107473BDBM107473(US8592410, 13)
Affinity DataIC50: 8.80nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107489BDBM107489(US8575157, 203 | US8598163, 73 | US8592410, Compar...)
Affinity DataIC50: 8.94nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107488BDBM107488(US8575157, 202 | US8598163, 72 | US8592410, Compar...)
Affinity DataIC50: 8.94nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107468BDBM107468(US8592410, 62 | US8592410, 3 | US8592410, 1)
Affinity DataIC50: 11.3nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50353392BDBM50353392(US8598163, 67 | US8575157, 197 | CHEMBL1829761 | U...)
Affinity DataIC50: 11.9nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107481BDBM107481(US8575157, 189 | US8598163, 59 | US8592410, Compar...)
Affinity DataIC50: 12.0nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107485BDBM107485(US8598163, 69 | US8575157, 199 | US8592410, Compar...)
Affinity DataIC50: 13.4nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107482BDBM107482(US8598163, 60 | US8575157, 190 | US8592410, Compar...)
Affinity DataIC50: 14.2nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107483BDBM107483(US8575157, 192 | US8598163, 62 | US8592410, Compar...)
Affinity DataIC50: 15.2nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 107470BDBM107470(US8592410, 9)
Affinity DataIC50: 16.4nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
US Patent

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