Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 6698
TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148179BDBM148179(US8962616, 7)
Affinity DataIC50: 55nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50012648BDBM50012648(CHEMBL3261057)
Affinity DataIC50: 59nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148176BDBM148176(US8962616, 22 | US8962616, 4)
Affinity DataIC50: 84nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148176BDBM148176(US8962616, 22 | US8962616, 4)
Affinity DataIC50: 89nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148186BDBM148186(US8962616, 15)
Affinity DataIC50: 112nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148192BDBM148192(US8962616, 23)
Affinity DataIC50: 161nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148174BDBM148174(US8962616, 2)
Affinity DataIC50: 183nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148179BDBM148179(US8962616, 7)
Affinity DataIC50: 185nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148178BDBM148178(US8962616, 6)
Affinity DataIC50: 198nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148185BDBM148185(US8962616, 13)
Affinity DataIC50: 208nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148180BDBM148180(US8962616, 8)
Affinity DataIC50: 260nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148176BDBM148176(US8962616, 22 | US8962616, 4)
Affinity DataIC50: 273nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148172BDBM148172(US8962616, 17)
Affinity DataIC50: 301nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148182BDBM148182(US8962616, 11)
Affinity DataIC50: 316nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148187BDBM148187(US8962616, 18)
Affinity DataIC50: 390nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148185BDBM148185(US8962616, 13)
Affinity DataIC50: 439nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148188BDBM148188(US8962616, 19)
Affinity DataIC50: 444nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148189BDBM148189(US8962616, 20)
Affinity DataIC50: 467nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148177BDBM148177(US8962616, 5)
Affinity DataIC50: 473nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148173BDBM148173(US8962616, 1)
Affinity DataIC50: 511nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148181BDBM148181(US8962616, 9)
Affinity DataIC50: 583nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148173BDBM148173(US8962616, 1)
Affinity DataIC50: 619nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148189BDBM148189(US8962616, 20)
Affinity DataIC50: 629nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148193BDBM148193(US8962616, 24)
Affinity DataIC50: 688nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148187BDBM148187(US8962616, 18)
Affinity DataIC50: 695nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148190BDBM148190(US8962616, 21)
Affinity DataIC50: 983nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148193BDBM148193(US8962616, 24)
Affinity DataIC50: 1.08E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148177BDBM148177(US8962616, 5)
Affinity DataIC50: 1.15E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148176BDBM148176(US8962616, 22 | US8962616, 4)
Affinity DataIC50: 1.40E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148183BDBM148183(US8962616, 12)
Affinity DataIC50: 1.47E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148182BDBM148182(US8962616, 11)
Affinity DataIC50: 2.02E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148184BDBM148184(US8962616, 14)
Affinity DataIC50: 2.21E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148178BDBM148178(US8962616, 6)
Affinity DataIC50: 2.37E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148186BDBM148186(US8962616, 15)
Affinity DataIC50: 2.82E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148190BDBM148190(US8962616, 21)
Affinity DataIC50: 3.09E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50012648BDBM50012648(CHEMBL3261057)
Affinity DataIC50: 4.55E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148174BDBM148174(US8962616, 2)
Affinity DataIC50: 4.74E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148172BDBM148172(US8962616, 17)
Affinity DataIC50: 5.56E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148175BDBM148175(US8962616, 3)
Affinity DataIC50: 7.78E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148180BDBM148180(US8962616, 8)
Affinity DataIC50: 9.72E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 148181BDBM148181(US8962616, 9)
Affinity DataIC50: 1.00E+5nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent