Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 6941
TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160674BDBM160674(US9045498, 16)
Affinity DataIC50: 19nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160676BDBM160676(US9045498, 18)
Affinity DataIC50: 20nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160676BDBM160676(US9045498, 18)
Affinity DataIC50: 36nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160670BDBM160670(US9045498, 12)
Affinity DataIC50: 60nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160668BDBM160668(US9045498, 10)
Affinity DataIC50: 64nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160678BDBM160678(US9045498, 20)
Affinity DataIC50: 68nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160666BDBM160666(US9045498, 8)
Affinity DataIC50: 76nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160667BDBM160667(US9045498, 9)
Affinity DataIC50: 76nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160675BDBM160675(US9045498, 17)
Affinity DataIC50: 82nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160669BDBM160669(US9045498, 11)
Affinity DataIC50: 107nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160674BDBM160674(US9045498, 16)
Affinity DataIC50: 108nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160677BDBM160677(US9045498, 19)
Affinity DataIC50: 150nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160663BDBM160663(US9045498, 5)
Affinity DataIC50: 320nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160671BDBM160671(US9045498, 13)
Affinity DataIC50: 342nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160673BDBM160673(US9045498, 15)
Affinity DataIC50: 376nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160673BDBM160673(US9045498, 15)
Affinity DataIC50: 423nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160660BDBM160660(US9045498, 2)
Affinity DataIC50: 445nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160662BDBM160662(US9045498, 4)
Affinity DataIC50: 854nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160672BDBM160672(US9045498, 14)
Affinity DataIC50: 967nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160659BDBM160659(US9045498, 1)
Affinity DataIC50: 1.22E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160665BDBM160665(US9045498, 7)
Affinity DataIC50: 1.78E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160664BDBM160664(US9045498, 6)
Affinity DataIC50: 2.33E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160662BDBM160662(US9045498, 4)
Affinity DataIC50: 2.52E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160660BDBM160660(US9045498, 2)
Affinity DataIC50: 2.80E+3nMpH: 4.5 T: 2°CAssay Description:This assay measures the inhibition of the BACE2 enzyme as it cleaves a non-native peptide. A synthetic substrate that can be cleaved by BACE2 having ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160661BDBM160661(US9045498, 3)
Affinity DataIC50: 5.55E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent