Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 7344
TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190520BDBM190520(US9181182, 47)
Affinity DataEC50:  2.40nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190526BDBM190526(US9181182, 56)
Affinity DataEC50:  2.90nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190527BDBM190527(US9181182, 51)
Affinity DataEC50:  3.5nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190523BDBM190523(US9181182, 48)
Affinity DataEC50:  6.70nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190503BDBM190503(US9181182, 34)
Affinity DataEC50:  6.80nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190518BDBM190518(US9181182, 65)
Affinity DataEC50:  7.40nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190514BDBM190514(US9181182, 50)
Affinity DataEC50:  17.9nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190519BDBM190519(US9181182, 43)
Affinity DataEC50:  18nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190515BDBM190515(US9181182, 55)
Affinity DataEC50:  31.6nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190524BDBM190524(US9181182, 52)
Affinity DataEC50:  34.5nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190518BDBM190518(US9181182, 65)
Affinity DataEC50:  39nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190525BDBM190525(US9181182, 54)
Affinity DataEC50:  43.8nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190522BDBM190522(US9181182, 44)
Affinity DataEC50:  48.1nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190504BDBM190504(US9181182, 35)
Affinity DataEC50:  54nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190521BDBM190521(US9181182, 46)
Affinity DataEC50:  88nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190520BDBM190520(US9181182, 47)
Affinity DataEC50:  96.5nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190513BDBM190513(US9181182, 49)
Affinity DataEC50:  114nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190503BDBM190503(US9181182, 34)
Affinity DataEC50:  129nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190501BDBM190501(US9181182, 8)
Affinity DataEC50:  131nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190519BDBM190519(US9181182, 43)
Affinity DataEC50:  310nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190507BDBM190507(US9181182, 40)
Affinity DataEC50:  344nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190505BDBM190505(US9181182, 36)
Affinity DataEC50:  501nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190512BDBM190512(US9181182, 10)
Affinity DataEC50: >510nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190502BDBM190502(US9181182, 7)
Affinity DataEC50:  783nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190500BDBM190500(US9181182, 9)
Affinity DataEC50: >860nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 60832BDBM60832(US9181182, 23)
Affinity DataEC50:  1.24E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190508BDBM190508(US9181182, 41(a))
Affinity DataEC50: >1.36E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190510BDBM190510(US9181182, 42)
Affinity DataEC50:  1.42E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190507BDBM190507(US9181182, 40)
Affinity DataEC50: >1.56E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190498BDBM190498(US9181182, 2)
Affinity DataEC50:  1.56E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190511BDBM190511(US9181182, 12)
Affinity DataEC50:  1.82E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190516BDBM190516(US9181182, 58)
Affinity DataEC50: >2.06E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190499BDBM190499(US9181182, 3)
Affinity DataEC50:  2.11E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190517BDBM190517(US9181182, 59)
Affinity DataEC50: >2.13E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190506BDBM190506(US9181182, 39)
Affinity DataEC50: >3.24E+3nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 60833BDBM60833(US9181182, 33)
Affinity DataEC50: >2.40E+4nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190497BDBM190497(US9181182, 1)
Affinity DataEC50: >2.50E+4nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 190509BDBM190509(US9181182, 41(b))
Affinity DataEC50: >2.90E+4nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 60835BDBM60835(US9181182, 63)
Affinity DataEC50: >4.00E+4nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Akaal Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 60834BDBM60834(US9181182, 30)
Affinity DataEC50: >5.54E+4nMT: 2°CAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent