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Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 8546
TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM50160879(CHEMBL3793392 | US9505736, (1S,2S,3S)-1-Fluoro-2-(...)
Affinity DataIC50:  10nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257503(US9505736, (1S,2S,3S)-1-Fluoro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50:  20nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257508(US9505736, (1S,2S,3S)-2-(4-(2-Cyclopropyloxazol- 5...)
Affinity DataIC50:  20nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM50161831(CHEMBL3793932 | US9505736, (1S,2S,3S)-1-Fluoro-N-h...)
Affinity DataIC50:  40nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM50160874(CHEMBL3794485 | US9505736, (1S,2S,3S)-2-(4-(5- (Di...)
Affinity DataIC50:  40nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257501(US9505736, (1S,2S,3S)-2-(4-Bromophenyl)-1- fluoro-...)
Affinity DataIC50:  60nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257509(US9505736, (1S,2R,3S)-1-Fluoro-2-(2-(4- fluorophen...)
Affinity DataIC50:  60nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM50155803(CHEMBL3793455 | US9505736, (1S,2S,3S)-1-Chloro-N-h...)
Affinity DataIC50:  110nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257511(US9505736, (1R,2R,3R)-1-Fluoro-2-(4-(5- fluoropyri...)
Affinity DataIC50:  410nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257505(US9505736, (1R,2R,3R)-1-Fluoro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50:  1.43E+3nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257504(US9505736, (1R,2R,3R)-1-Chloro-N-hydroxy-2-(4-(5- ...)
Affinity DataIC50:  1.58E+3nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257507(US9505736, (1R,2S,3S)-2-(4-(2-Cyclopropyloxazol- 5...)
Affinity DataIC50:  4.65E+3nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257502(US9505736, (1R,2S,3S)-2-(8-Chloro-2,3- dihydrobenz...)
Affinity DataIC50:  6.47E+3nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257510(US9505736, (1R,2R,3R)-1-Fluoro-N-hydroxy-2-phenyl-...)
Affinity DataIC50:  6.87E+3nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257506(US9505736, (1R,2R,3R)-2-(4-(5- (Difluoromethoxy)py...)
Affinity DataIC50:  2.60E+4nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257512(US9505736, (1R,2S,3S)-2-(2-Cyclopropylpyridin-4- y...)
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 25°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent