Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 183
TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204807BDBM204807(US9546168, ex 16)
Affinity DataIC50: 0.230nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204806BDBM204806(US9546168, ex 15)
Affinity DataIC50: 0.290nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204804BDBM204804(US9546168, ex 13)
Affinity DataIC50: 0.310nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204788BDBM204788(US9546168, ex 1)
Affinity DataIC50: 0.370nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204805BDBM204805(US9546168, ex 14)
Affinity DataIC50: 0.390nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204791BDBM204791(US9546168, ex 4)
Affinity DataIC50: 0.390nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204802BDBM204802(US9546168, ex 11)
Affinity DataIC50: 0.450nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204821BDBM204821(US9546168, ex 23)
Affinity DataIC50: 0.490nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204817BDBM204817(US9546168, ex 19)
Affinity DataIC50: 0.530nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204800BDBM204800(US9546168, ex 10)
Affinity DataIC50: 0.660nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204792BDBM204792(US9546168, ex 5)
Affinity DataIC50: 0.720nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204799BDBM204799(US9546168, ex 9)
Affinity DataIC50: 0.75nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204820BDBM204820(US9546168, ex 22)
Affinity DataIC50: 0.75nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204796BDBM204796(US9546168, ex 7)
Affinity DataIC50: 0.830nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204798BDBM204798(US9546168, ex 8)
Affinity DataIC50: 0.910nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204790BDBM204790(US9546168, ex 3)
Affinity DataIC50: 0.920nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204818BDBM204818(US9546168, ex 20)
Affinity DataIC50: 1.13nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204789BDBM204789(US9546168, ex 2)
Affinity DataIC50: 1.24nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204822BDBM204822(US9546168, ex 24)
Affinity DataIC50: 1.25nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204803BDBM204803(US9546168, ex 12)
Affinity DataIC50: 1.64nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204824BDBM204824(US9546168, ex 25)
Affinity DataIC50: 1.85nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204812BDBM204812(US9546168, ex 18)
Affinity DataIC50: 3.70nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204795BDBM204795(US9546168, ex 6)
Affinity DataIC50: 4.34nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204825BDBM204825(US9546168, ex 27 | US9546168, ex 26)
Affinity DataIC50: 5.52nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204819BDBM204819(US9546168, ex 21)
Affinity DataIC50: 6.10nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204809BDBM204809(US9546168, ex 17)
Affinity DataIC50: 8.64nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204825BDBM204825(US9546168, ex 27 | US9546168, ex 26)
Affinity DataIC50: 12.7nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204925BDBM204925(US9546168, ex 29)
Affinity DataIC50: 13.3nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 204827BDBM204827(US9546168, ex 28)
Affinity DataIC50: 14.1nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC.sub.50) of each compound was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
US Patent