Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 209
TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228128BDBM228128(US9556191, example 35 | (e)-n-(4-((3-chloro-2,4-di...)
Affinity DataIC50: 0.900nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228125BDBM228125(US9556191, example 32 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228126BDBM228126(US9556191, example 33 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 1.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228119BDBM228119(US9556191, example 26 | (e)-n-(4-((1-(3-fluorobenz...)
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228121BDBM228121(US9556191, example 28 | (e)-n-(7-ethoxy-4-((1-(3-f...)
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228117BDBM228117(US9556191, example 24 | (e)-n-(4-((3-chloro-4-(pyr...)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228111BDBM228111(US9556191, example 6 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228116BDBM228116(US9556191, example 23 | (e)-n-(4-((3-chloro-4-(pyr...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228115BDBM228115(US9556191, example 22 | (e)-n-(4-((3-chloro-4-(pyr...)
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228124BDBM228124(US9556191, example 31 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 2.10nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228120BDBM228120(US9556191, example 27 | (e)-n-(4-((1-(3-fluorobenz...)
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228118BDBM228118(US9556191, example 25 | (e)-n-(4-((3-chloro-4-(pyr...)
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228107BDBM228107(US9556191, example 1 | (E)-N-(4-((3-Chloro-4-fluo...)
Affinity DataIC50: 3.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228127BDBM228127(US9556191, example 34 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228114BDBM228114(US9556191, example 21 | (e)-n-(4-((3-chloro-4-((3-...)
Affinity DataIC50: 3.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228110BDBM228110(US9556191, example 5 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 3.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228122BDBM228122(US9556191, example 29 | (e)-n-(4-((3-chloro-4-((3-...)
Affinity DataIC50: 3.70nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228125BDBM228125(US9556191, example 32 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228117BDBM228117(US9556191, example 24 | (e)-n-(4-((3-chloro-4-(pyr...)
Affinity DataIC50: 4.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228108BDBM228108(US9556191, example 2 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 4.30nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228113BDBM228113(US9556191, example 20 | (e)-n-(4-((3-chloro-4-fluo...)
Affinity DataIC50: 4.80nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228126BDBM228126(US9556191, example 33 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228118BDBM228118(US9556191, example 25 | (e)-n-(4-((3-chloro-4-(pyr...)
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228109BDBM228109(US9556191, example 3 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 6.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228109BDBM228109(US9556191, example 3 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 6.40nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228124BDBM228124(US9556191, example 31 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 6.40nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228123BDBM228123(US9556191, example 30 | (e)-n-(4-((3-chloro-4-((3-...)
Affinity DataIC50: 6.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228110BDBM228110(US9556191, example 5 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 6.80nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228125BDBM228125(US9556191, example 32 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228127BDBM228127(US9556191, example 34 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228120BDBM228120(US9556191, example 27 | (e)-n-(4-((1-(3-fluorobenz...)
Affinity DataIC50: 7.90nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228109BDBM228109(US9556191, example 3 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 8.10nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228107BDBM228107(US9556191, example 1 | (E)-N-(4-((3-Chloro-4-fluo...)
Affinity DataIC50: 8.30nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228116BDBM228116(US9556191, example 23 | (e)-n-(4-((3-chloro-4-(pyr...)
Affinity DataIC50: 8.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228118BDBM228118(US9556191, example 25 | (e)-n-(4-((3-chloro-4-(pyr...)
Affinity DataIC50: 8.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228111BDBM228111(US9556191, example 6 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 8.70nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228124BDBM228124(US9556191, example 31 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 9.10nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228126BDBM228126(US9556191, example 33 | (e)-n-(4-((3,4-dichloro-2-...)
Affinity DataIC50: 9.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228111BDBM228111(US9556191, example 6 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 10.4nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228110BDBM228110(US9556191, example 5 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 11.7nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228113BDBM228113(US9556191, example 20 | (e)-n-(4-((3-chloro-4-fluo...)
Affinity DataIC50: 12.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228119BDBM228119(US9556191, example 26 | (e)-n-(4-((1-(3-fluorobenz...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228107BDBM228107(US9556191, example 1 | (E)-N-(4-((3-Chloro-4-fluo...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228121BDBM228121(US9556191, example 28 | (e)-n-(7-ethoxy-4-((1-(3-f...)
Affinity DataIC50: 14.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228114BDBM228114(US9556191, example 21 | (e)-n-(4-((3-chloro-4-((3-...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228112BDBM228112(US9556191, example 7 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 15.4nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228113BDBM228113(US9556191, example 20 | (e)-n-(4-((3-chloro-4-fluo...)
Affinity DataIC50: 15.8nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228108BDBM228108(US9556191, example 2 | (e)-n-(4-((3-chloro-4-fluor...)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228128BDBM228128(US9556191, example 35 | (e)-n-(4-((3-chloro-2,4-di...)
Affinity DataIC50: 17.8nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 228117BDBM228117(US9556191, example 24 | (e)-n-(4-((3-chloro-4-(pyr...)
Affinity DataIC50: 18.4nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
US Patent

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