Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 777
TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290222BDBM290222(US9573958, Compound 20)
Affinity DataIC50: 0.600nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290224BDBM290224(US9573958, Compound 59)
Affinity DataIC50: 0.600nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290254BDBM290254(US9573958, Compound 63)
Affinity DataIC50: 1.30nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290231BDBM290231(US9573958, Compound 22)
Affinity DataIC50: 1.80nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290167BDBM290167(US9573958, Compound 113)
Affinity DataIC50: 2.30nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290232BDBM290232(US9573958, Compound 61)
Affinity DataIC50: 2.40nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290242BDBM290242(US9573958, Compound 134)
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290226BDBM290226(US9573958, Compound 21)
Affinity DataIC50: 3nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290235BDBM290235(US9573958, Compound 62)
Affinity DataIC50: 3.5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290185BDBM290185(US9573958, Compound 49)
Affinity DataIC50: 5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290229BDBM290229(US9573958, Compound 60)
Affinity DataIC50: 5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290257BDBM290257(US9573958, Compound 64)
Affinity DataIC50: 5.40nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290164BDBM290164(US9573958, Compound 40)
Affinity DataIC50: 5.60nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290248BDBM290248(US9573958, Compound 136)
Affinity DataIC50: 6nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290149BDBM290149(US9573958, Compound 33)
Affinity DataIC50: 7nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290217BDBM290217(US9573958, Compound 58)
Affinity DataIC50: 7nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290258BDBM290258(US9573958, Compound 85)
Affinity DataIC50: 7.5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290142BDBM290142(US9573958, Compound 102)
Affinity DataIC50: 7.60nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290181BDBM290181(US9573958, Compound 117)
Affinity DataIC50: 9.30nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290216BDBM290216(US9573958, Compound 19)
Affinity DataIC50: 10nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290171BDBM290171(US9573958, Compound 42)
Affinity DataIC50: 10nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290173BDBM290173(US9573958, Compound 116)
Affinity DataIC50: 10.3nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290186BDBM290186(US9573958, Compound 118)
Affinity DataIC50: 11.8nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290243BDBM290243(US9573958, Compound 26)
Affinity DataIC50: 12nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290193BDBM290193(US9573958, Compound 51)
Affinity DataIC50: 13nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290233BDBM290233(US9573958, Compound 128)
Affinity DataIC50: 13.7nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290161BDBM290161(US9573958, Compound 115)
Affinity DataIC50: 14.5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290230BDBM290230(US9573958, Compound 127)
Affinity DataIC50: 18nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290237BDBM290237(US9573958, Compound 24)
Affinity DataIC50: 19nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290245BDBM290245(US9573958, Compound 135)
Affinity DataIC50: 19nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290179BDBM290179(US9573958, Compound 44)
Affinity DataIC50: 19.9nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290158BDBM290158(US9573958, Compound 37)
Affinity DataIC50: 20nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290234BDBM290234(US9573958, Compound 23)
Affinity DataIC50: 23nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290256BDBM290256(US9573958, Compound 87)
Affinity DataIC50: 24.8nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290150BDBM290150(US9573958, Compound 108)
Affinity DataIC50: 26nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290239BDBM290239(US9573958, Compound 132)
Affinity DataIC50: 28nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290203BDBM290203(US9573958, Compound 18)
Affinity DataIC50: 28nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290194BDBM290194(US9573958, Compound 121)
Affinity DataIC50: 35nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290189BDBM290189(US9573958, Compound 50)
Affinity DataIC50: 37nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290155BDBM290155(US9573958, Compound 36)
Affinity DataIC50: 40nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290255BDBM290255(US9573958, Compound 86)
Affinity DataIC50: 44nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290253BDBM290253(US9573958, Compound 89)
Affinity DataIC50: 49nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290198BDBM290198(US9573958, Compound 122)
Affinity DataIC50: 52nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290251BDBM290251(US9573958, Compound 138)
Affinity DataIC50: 68nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290183BDBM290183(US9573958, Compound 12)
Affinity DataIC50: 120nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290197BDBM290197(US9573958, Compound 53)
Affinity DataIC50: 120nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290238BDBM290238(US9573958, Compound 68)
Affinity DataIC50: 127nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290195BDBM290195(US9573958, Compound 17)
Affinity DataIC50: 130nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290240BDBM290240(US9573958, Compound 25)
Affinity DataIC50: 137nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290134BDBM290134(US9573958, Compound 32)
Affinity DataIC50: 142nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

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