Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 1309
TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 25117BDBM25117(AG-013736 | N-methyl-2-({3-[(E)-2-(pyridin-2-yl)et...)
Affinity DataIC50: 0.910nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316168BDBM316168(2-[(3-{[4-(3-{2-[2-(2-aminoethoxy)ethoxy]ethyl}ure...)
Affinity DataIC50: 2.80nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316167BDBM316167(2-[(3-{[4-(3-{2-[2-(2-hydroxyethoxy)ethoxy]ethyl}u...)
Affinity DataIC50: 2.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316133BDBM316133(2-[(3-{[4-(3-{2-[2-(2-methoxyethoxy)ethoxy]ethyl}u...)
Affinity DataIC50: 3.10nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316132BDBM316132(2-({3-[(4-{3-[2-(2-methoxyethoxy)ethyl]ureido}phen...)
Affinity DataIC50: 3.40nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
Ligand InfoPC sidSimilars
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316169BDBM316169(2-{[3-({4-[3-(2-{2-[2-(dimethylamino)ethoxy]ethoxy...)
Affinity DataIC50: 3.5nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316151BDBM316151(2-({3-[(4-{[2-(2-methoxyethoxy)ethyl]amino}phenyl)...)
Affinity DataIC50: 3.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316153BDBM316153(2-{[3-({4-[(2,5,8,11-tetraoxatridecane-13-yl)amino...)
Affinity DataIC50: 3.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316135BDBM316135(2-{[3-({4-[3-(2,5,8,11,14-pentaoxahexadecane-16-yl...)
Affinity DataIC50: 3.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316134BDBM316134(2-{[3-({4-[3-(2,5,8,11-tetraoxatridecane-13-yl)ure...)
Affinity DataIC50: 3.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 312269BDBM312269(2-{[3-({3-[3-(2-methoxyethyl)ureido]phenyl}ethynyl...)
Affinity DataIC50: 4nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316152BDBM316152(2-[(3-{[4-({2-[2-(2-methoxyethoxy)ethoxy]ethyl}ami...)
Affinity DataIC50: 4nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316145BDBM316145(N-{4-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 4.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316160BDBM316160(2-[(3-{[5-(3-{2-[2-(2-methoxyethoxy)ethoxy]ethyl}u...)
Affinity DataIC50: 4.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316154BDBM316154(2-{[3-({4-[(2,5,8,11,14-pentaoxahexadecane-16-yl)a...)
Affinity DataIC50: 4.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316166BDBM316166(N-{6-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 4.30nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316131BDBM316131(2-{[3-({4-[3-(2-methoxyethyl)ureido]phenyl}ethynyl...)
Affinity DataIC50: 4.5nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316144BDBM316144(N-{3-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 4.60nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316072BDBM316072(2-({3-[(3-{3-[2-(2-methoxyethoxy)ethyl]ureido}phen...)
Affinity DataIC50: 4.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316147BDBM316147(N-{4-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 4.80nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316146BDBM316146(N-{4-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 4.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316170BDBM316170(2-[(3-{[4-(3-{2-[2-(2-acetamideethoxy)ethoxy]ethyl...)
Affinity DataIC50: 5.10nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316141BDBM316141(2-[2-(2-methoxyethoxy)ethoxy]ethyl {4-[(6-{[2-(met...)
Affinity DataIC50: 5.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316157BDBM316157(2-[(3-{[6-(3-{2-[2-(2-methoxyethoxy)ethoxy] ethyl}...)
Affinity DataIC50: 5.5nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316173BDBM316173(6-[2-(methylcarbamoyl)phenylsulfanyl]-3-[2-(pyridi...)
Affinity DataIC50: 5.5nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316161BDBM316161(2-{[3-({5-[3-(2,5,8,11-tetraoxatridecane-13-yl)ure...)
Affinity DataIC50: 5.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316140BDBM316140(2-(2-methoxyethoxy)ethyl {4-[(6-{[2-(methylcarbamo...)
Affinity DataIC50: 5.80nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316083BDBM316083(2-[(3-{[3-(3-{2-[2-(2-methoxyethoxy)ethoxy]ethyl}u...)
Affinity DataIC50: 5.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316162BDBM316162(2-{[3-({5-[3-(2,5,8,11,14-pentaoxahexadecane-16-yl...)
Affinity DataIC50: 5.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316171BDBM316171(N-methyl-2-[(3-{[4-(3-{2-[2-(2-morpholinoethoxy)et...)
Affinity DataIC50: 6.10nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316142BDBM316142(2,5,8,11-tetraoxatridecane-13-yl {4-[(6-{[2-(methy...)
Affinity DataIC50: 6.40nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316085BDBM316085(2-{[(3-({3-[3-(2,5,8,11-tetraoxatridecane-13-yl)ur...)
Affinity DataIC50: 6.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316137BDBM316137(2-(2-methoxyethoxy)ethyl {3-[(6-{[2-(methylcarbamo...)
Affinity DataIC50: 7.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316139BDBM316139(2-methoxyethyl {4-[(6-{[2-(methylcarbamoyl)phenyl]...)
Affinity DataIC50: 7.60nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316130BDBM316130(2-{[3-({3-[3-(2,5,8,11,14-pentaoxahexadecane-16-yl...)
Affinity DataIC50: 7.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316163BDBM316163(N-{5-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 7.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316143BDBM316143(2,5,8,11,14-pentaoxahexadecane-16-yl {4-[(6-{[2-(m...)
Affinity DataIC50: 8nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316136BDBM316136(2-methoxyethyl {3-[(6-{[2-(methylcarbamoyl)phenyl]...)
Affinity DataIC50: 8.80nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316155BDBM316155(2-[(3-{[5-(3-{2-[2-(2-methoxyethoxy)ethoxy]ethyl}u...)
Affinity DataIC50: 8.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316138BDBM316138(2-[2-(2-methoxyethoxy)ethoxy]ethyl {3-[(6-{[2-(met...)
Affinity DataIC50: 8.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316158BDBM316158(2-{[3-({6-[3-(2,5,8,11-tetraoxatridecane-13-yl)ure...)
Affinity DataIC50: 9.20nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316164BDBM316164(N-{5-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 9.70nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316149BDBM316149(2-({3-[(3-{[2-(2-methoxyethoxy)ethyl]amino}phenyl)...)
Affinity DataIC50: 9.90nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316150BDBM316150(2-[(3-{[3-({2-[2-(2-methoxyethoxy)ethoxy]ethyl}ami...)
Affinity DataIC50: 10nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316159BDBM316159(2-{[3-({6-[3-(2,5,8,11,14-pentaoxahexadecane-16-yl...)
Affinity DataIC50: 11nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316165BDBM316165(N-{5-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-inda...)
Affinity DataIC50: 12nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316148BDBM316148(2-{[3-({3-[(2-methoxyethyl)amino]phenyl}ethynyl)-1...)
Affinity DataIC50: 13nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 316156BDBM316156(2-{[3-({5-[3-(2,5,8,11,14-pentaoxahexadecane-16-yl...)
Affinity DataIC50: 15nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent