Compile Data Set for Download or QSAR
Report error Found 463 Enz. Inhib. hit(s) with all data for entry = 10033
TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509793BDBM509793(US11124497, Compound 143 | US11524940, Compound 14...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509857BDBM509857(US11124497, Compound 383 | US11524940, Compound 38...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509857BDBM509857(US11124497, Compound 383 | US11524940, Compound 38...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509796BDBM509796(US11124497, Compound 149 | US11524940, Compound 14...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509859BDBM509859(US11124497, Compound 385 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509799BDBM509799(US11124497, Compound 167 | US11472793, Compound 16...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509799BDBM509799(US11124497, Compound 167 | US11472793, Compound 16...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509927BDBM509927(US11124497, Compound 513 (Isomer 1) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509873BDBM509873(US11124497, Compound 433 | US11472793, Compound 43...)
Affinity DataEC50:  6.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509927BDBM509927(US11124497, Compound 513 (Isomer 1) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509801BDBM509801(US11124497, Compound 183 | US11524940, Compound 18...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509928BDBM509928(US11124497, Compound 513 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509850BDBM509850(US11124497, Compound 365 (Isomer 1) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509835BDBM509835(US11124497, Compound 327)
Affinity DataEC50:  6.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509851BDBM509851(US11124497, Compound 365 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509790BDBM509790(US11124497, Compound 135 (Isomer 1) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509853BDBM509853(US11124497, Compound 369 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509790BDBM509790(US11124497, Compound 135 (Isomer 1) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509853BDBM509853(US11124497, Compound 369 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509793BDBM509793(US11124497, Compound 143 | US11524940, Compound 14...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509872BDBM509872(US11124497, Compound 407 | US11524940, Compound 40...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509811BDBM509811(BDBM550827 | US11124497, Compound 227)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509940BDBM509940(US11124497, Compound 591 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509877BDBM509877(US11124497, Compound 449 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509942BDBM509942(US11124497, Compound 598 | US11524940, Compound 59...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509815BDBM509815(US11124497, Compound 245 | US11524940, Compound 24...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509879BDBM509879(US11124497, Compound 451 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509817BDBM509817(US11124497, Compound 253 | US11524940, Compound 25...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509804BDBM509804(US11124497, Compound 201 | US11524940, Compound 20...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509804BDBM509804(US11124497, Compound 201 | US11524940, Compound 20...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509932BDBM509932(US11124497, Compound 535 | US11524940, Compound 53...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509928BDBM509928(US11124497, Compound 513 (Isomer 2) | US11524940, ...)
Affinity DataEC50:  6.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509806BDBM509806(US11124497, Compound 209 | US11524940, Compound 20...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509869BDBM509869(US11124497, Compound 401 (Isomer 1) | US11124497, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509934BDBM509934(US11124497, Compound 551 | US11524940, Compound 55...)
Affinity DataEC50:  6.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509869BDBM509869(US11124497, Compound 401 (Isomer 1) | US11124497, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509829BDBM509829(US11124497, Compound 273C | US11524940, Compound 2...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509895BDBM509895(US11124497, Compound 475 (Isomer 1) | US11312704, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509896BDBM509896(US11124497, Compound 475 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509817BDBM509817(US11124497, Compound 253 | US11524940, Compound 25...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509818BDBM509818(US11124497, Compound 265 | US11524940, Compound 26...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509818BDBM509818(US11124497, Compound 265 | US11524940, Compound 26...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509949BDBM509949(US11124497, Compound 649 | US11524940, Compound 64...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509885BDBM509885(US11124497, Compound 465 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509949BDBM509949(US11124497, Compound 649 | US11524940, Compound 64...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509886BDBM509886(US11124497, Compound 467 (Isomer 1) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509886BDBM509886(US11124497, Compound 467 (Isomer 1) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509782BDBM509782(US11124497, Compound 127 | US11124497, Compound 13...)
Affinity DataEC50:  6.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509784BDBM509784(US11124497, Compound 131 | US11524940, Compound 13...)
Affinity DataEC50:  6.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 509845BDBM509845(US11124497, Compound 355 | US11524940, Compound 35...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

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