Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50008518
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074007(6-(3,5-dimethyl-4-isoxazolylsulfonamido)-1'-[2-(1-...)
Affinity DataKi:  0.690nMAssay Description:Ability of the compound to displace [125I]-HEAT from cloned human Alpha-1A adrenergic receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074009(CHEMBL431631 | N-[1'-(2-methoxyphenethyl)-4-oxospi...)
Affinity DataKi:  6.5nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074012(6-(1-methyl-1H-4-imidazolylsulfonamido)-1'-[2-(1-n...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074008(CHEMBL98430 | N-[1'-[2-(2-methyl-1H-3-indolyl)ethy...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074007(6-(3,5-dimethyl-4-isoxazolylsulfonamido)-1'-[2-(1-...)
Affinity DataKi:  10nMAssay Description:Binding affinity of the compound against Alpha-1A adrenergic receptor in human prostatic tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50074007(6-(3,5-dimethyl-4-isoxazolylsulfonamido)-1'-[2-(1-...)
Affinity DataKi:  10nMAssay Description:Binding affinity of the compound against Alpha-1A adrenergic receptor in rat prostatic tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074006(CHEMBL322688 | N-[1'-[2-(1-naphthyl)ethyl]-4-oxosp...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074007(6-(3,5-dimethyl-4-isoxazolylsulfonamido)-1'-[2-(1-...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074013(CHEMBL99614 | N-[1'-[2-(1-naphthyl)ethyl]-4-oxospi...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074012(6-(1-methyl-1H-4-imidazolylsulfonamido)-1'-[2-(1-n...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074007(6-(3,5-dimethyl-4-isoxazolylsulfonamido)-1'-[2-(1-...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074006(CHEMBL322688 | N-[1'-[2-(1-naphthyl)ethyl]-4-oxosp...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074011(1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-inden...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074003(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-1H-isoch...)
Affinity DataKi:  45nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074014(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-2H-chrom...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074011(1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-inden...)
Affinity DataKi:  49nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074010(1'-[2-(1-naphthyl)ethyl]spiro[2H-chromene-2,4'-(he...)
Affinity DataKi:  53nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074014(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-2H-chrom...)
Affinity DataKi:  53nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074012(6-(1-methyl-1H-4-imidazolylsulfonamido)-1'-[2-(1-n...)
Affinity DataKi:  53nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074006(CHEMBL322688 | N-[1'-[2-(1-naphthyl)ethyl]-4-oxosp...)
Affinity DataKi:  53nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074002(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-2H-chrom...)
Affinity DataKi:  55nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074002(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-2H-chrom...)
Affinity DataKi:  56nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074003(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-1H-isoch...)
Affinity DataKi:  60nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074014(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-2H-chrom...)
Affinity DataKi:  67nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074010(1'-[2-(1-naphthyl)ethyl]spiro[2H-chromene-2,4'-(he...)
Affinity DataKi:  71nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074009(CHEMBL431631 | N-[1'-(2-methoxyphenethyl)-4-oxospi...)
Affinity DataKi:  94nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074002(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-2H-chrom...)
Affinity DataKi:  99nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074008(CHEMBL98430 | N-[1'-[2-(2-methyl-1H-3-indolyl)ethy...)
Affinity DataKi:  115nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074013(CHEMBL99614 | N-[1'-[2-(1-naphthyl)ethyl]-4-oxospi...)
Affinity DataKi:  136nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074003(1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-1H-isoch...)
Affinity DataKi:  137nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074013(CHEMBL99614 | N-[1'-[2-(1-naphthyl)ethyl]-4-oxospi...)
Affinity DataKi:  149nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074011(1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-inden...)
Affinity DataKi:  149nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074009(CHEMBL431631 | N-[1'-(2-methoxyphenethyl)-4-oxospi...)
Affinity DataKi:  175nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074010(1'-[2-(1-naphthyl)ethyl]spiro[2H-chromene-2,4'-(he...)
Affinity DataKi:  200nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074008(CHEMBL98430 | N-[1'-[2-(2-methyl-1H-3-indolyl)ethy...)
Affinity DataKi:  221nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074004(1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chrome...)
Affinity DataKi:  793nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074004(1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chrome...)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074004(1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chrome...)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074005(CHEMBL419164 | N-[4-oxo-1'-[2-(2-pyridyl)ethyl]spi...)
Affinity DataKi:  1.67E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50003331(CHEMBL101322 | CHEMBL1204312 | N-[4-oxo-1'-[2-(2-p...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074005(CHEMBL419164 | N-[4-oxo-1'-[2-(2-pyridyl)ethyl]spi...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50003331(CHEMBL101322 | CHEMBL1204312 | N-[4-oxo-1'-[2-(2-p...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50074005(CHEMBL419164 | N-[4-oxo-1'-[2-(2-pyridyl)ethyl]spi...)
Affinity DataKi:  3.25E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50003331(CHEMBL101322 | CHEMBL1204312 | N-[4-oxo-1'-[2-(2-p...)
Affinity DataKi:  3.84E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed