Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50008554
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50:  1nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074664((S)-N-[(S)-1-((S)-2-Carbamoyl-pyrrolidine-1-carbon...)
Affinity DataIC50:  1nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50422305(CHEMBL1791268)
Affinity DataIC50:  1nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074660((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-ph...)
Affinity DataIC50:  3nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50:  4nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074658((S)-1-{(S)-2-[(S)-2-((S)-6-(6-Amino-hexanoylamino)...)
Affinity DataIC50:  4nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50422305(CHEMBL1791268)
Affinity DataIC50:  5nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074664((S)-N-[(S)-1-((S)-2-Carbamoyl-pyrrolidine-1-carbon...)
Affinity DataIC50:  8nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50:  18nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074658((S)-1-{(S)-2-[(S)-2-((S)-6-(6-Amino-hexanoylamino)...)
Affinity DataIC50:  20nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074660((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-ph...)
Affinity DataIC50:  30nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074666((S)-2-((S)-2-{(S)-2-[2-(4-Benzyloxycarbonylamino-p...)
Affinity DataIC50:  30nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50:  68nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074666((S)-2-((S)-2-{(S)-2-[2-(4-Benzyloxycarbonylamino-p...)
Affinity DataIC50:  200nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074667((S)-2-((S)-2-{(S)-2-[2-(4-Benzoylamino-phenyl)-ace...)
Affinity DataIC50:  295nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074665((S)-2-((S)-3-Carboxy-2-{(S)-2-[2-(4-hydroxy-phenyl...)
Affinity DataIC50:  430nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074669((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-phenylacety...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of integrin alpha4-beta7 adhesion to JY cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074667((S)-2-((S)-2-{(S)-2-[2-(4-Benzoylamino-phenyl)-ace...)
Affinity DataIC50:  3.25E+3nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074665((S)-2-((S)-3-Carboxy-2-{(S)-2-[2-(4-hydroxy-phenyl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of integrin alpha4-beta7 adhesion to JY cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074662((S)-2-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074669((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-phenylacety...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ICAM-1 transfected CHO cell adhesion to integrin alphaL-beta2 of human JY cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074662((S)-2-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of integrin alpha4-beta7 adhesion to JY cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074670((S)-2-{(S)-2-[(S)-2-((2S,3S)-2-Amino-3-methyl-pent...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of integrin alpha4-beta1 binding to VCAM-IgMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of integrin alphaIIb-beta3 adhesion to human citreated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of integrin alpha1-beta1 adhesion using K562 cells expressing alpha-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of integrin alphaIIb-beta3 adhesion to human citreated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ICAM-1 transfected CHO cell adhesion to integrin alphaL-beta2 of human JY cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of integrin alpha5-beta1 adhesion to K562 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ICAM-1 transfected CHO cell adhesion to integrin alphaL-beta2 of human JY cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of integrin alphaIIb-beta3 adhesion to human citreated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074659((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of integrin alpha5-beta1 adhesion to K562 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074668((S)-2-((S)-4-Methyl-2-{2-[4-(3-o-tolyl-ureido)-phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of integrin alpha5-beta1 adhesion to K562 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50074670((S)-2-{(S)-2-[(S)-2-((2S,3S)-2-Amino-3-methyl-pent...)
Affinity DataIC50:  1.75E+5nMAssay Description:Inhibition of integrin alpha4-beta1 adhesion to Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed