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Found 76 Enz. Inhib. hit(s) with all data for entry = 50008564
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074724(6-(2-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  14nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074735(6-(3-(trifluoromethoxy)benzyl)-5,6,7,8-tetrahydroq...)
Affinity DataIC50:  14nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  15nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  17nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074725(6-tert-Butyl-5,6,7,8-tetrahydro-quinazoline-2,4-di...)
Affinity DataIC50:  18nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074720(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  21nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074718(6-(3-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  21nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074727(6-(2-Methyl-benzyl)-5,6,7,8-tetrahydro-quinazoline...)
Affinity DataIC50:  23nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074719(6-(3,4-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  23nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074721(6-(3,4,5-Trimethoxy-benzyl)-5,6,7,8-tetrahydro-qui...)
Affinity DataIC50:  24nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50:  31nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074723(6-Benzyl-5,6,7,8-tetrahydro-quinazoline-2,4-diamin...)
Affinity DataIC50:  32nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074720(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  34nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074722(6-(3-Methyl-benzyl)-5,6,7,8-tetrahydro-quinazoline...)
Affinity DataIC50:  36nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074721(6-(3,4,5-Trimethoxy-benzyl)-5,6,7,8-tetrahydro-qui...)
Affinity DataIC50:  38nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074732(6-(Tetrahydro-furan-2-ylmethyl)-5,6,7,8-tetrahydro...)
Affinity DataIC50:  40nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074728(6-(thiophen-3-ylmethyl)-5,6,7,8-tetrahydroquinazol...)
Affinity DataIC50:  49nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074734(6-(4-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  50nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50033539(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-5,6,7,8-...)
Affinity DataIC50:  54nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074720(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  57nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074737(6-Thiophen-2-ylmethyl-5,6,7,8-tetrahydro-quinazoli...)
Affinity DataIC50:  62nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074719(6-(3,4-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  63nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074725(6-tert-Butyl-5,6,7,8-tetrahydro-quinazoline-2,4-di...)
Affinity DataIC50:  65nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074726(6-(4-(trifluoromethoxy)benzyl)-5,6,7,8-tetrahydroq...)
Affinity DataIC50:  73nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074734(6-(4-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  77nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074735(6-(3-(trifluoromethoxy)benzyl)-5,6,7,8-tetrahydroq...)
Affinity DataIC50:  79nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074737(6-Thiophen-2-ylmethyl-5,6,7,8-tetrahydro-quinazoli...)
Affinity DataIC50:  80nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074721(6-(3,4,5-Trimethoxy-benzyl)-5,6,7,8-tetrahydro-qui...)
Affinity DataIC50:  91nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074719(6-(3,4-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  100nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074735(6-(3-(trifluoromethoxy)benzyl)-5,6,7,8-tetrahydroq...)
Affinity DataIC50:  100nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074727(6-(2-Methyl-benzyl)-5,6,7,8-tetrahydro-quinazoline...)
Affinity DataIC50:  110nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074718(6-(3-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  110nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074722(6-(3-Methyl-benzyl)-5,6,7,8-tetrahydro-quinazoline...)
Affinity DataIC50:  110nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074724(6-(2-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  120nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074728(6-(thiophen-3-ylmethyl)-5,6,7,8-tetrahydroquinazol...)
Affinity DataIC50:  130nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074731(6-(3-(trifluoromethyl)benzyl)-5,6,7,8-tetrahydroqu...)
Affinity DataIC50:  140nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074726(6-(4-(trifluoromethoxy)benzyl)-5,6,7,8-tetrahydroq...)
Affinity DataIC50:  170nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074723(6-Benzyl-5,6,7,8-tetrahydro-quinazoline-2,4-diamin...)
Affinity DataIC50:  180nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50033549(6-[(2,5-Dimethoxy-phenylamino)-methyl]-5,6,7,8-tet...)
Affinity DataIC50:  180nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074725(6-tert-Butyl-5,6,7,8-tetrahydro-quinazoline-2,4-di...)
Affinity DataIC50:  180nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074731(6-(3-(trifluoromethyl)benzyl)-5,6,7,8-tetrahydroqu...)
Affinity DataIC50:  190nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074738(6-(3,4,5-Trimethoxy-benzyl)-5,6,7,8-tetrahydro-pyr...)
Affinity DataIC50:  200nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074737(6-Thiophen-2-ylmethyl-5,6,7,8-tetrahydro-quinazoli...)
Affinity DataIC50:  210nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074727(6-(2-Methyl-benzyl)-5,6,7,8-tetrahydro-quinazoline...)
Affinity DataIC50:  250nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074718(6-(3-Methoxy-benzyl)-5,6,7,8-tetrahydro-quinazolin...)
Affinity DataIC50:  270nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074732(6-(Tetrahydro-furan-2-ylmethyl)-5,6,7,8-tetrahydro...)
Affinity DataIC50:  270nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074723(6-Benzyl-5,6,7,8-tetrahydro-quinazoline-2,4-diamin...)
Affinity DataIC50:  290nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50033539(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-5,6,7,8-...)
Affinity DataIC50:  290nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074729(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50:  300nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074722(6-(3-Methyl-benzyl)-5,6,7,8-tetrahydro-quinazoline...)
Affinity DataIC50:  340nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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