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Found 15 Enz. Inhib. hit(s) with all data for entry = 50008577
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074976(2-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...)
Affinity DataIC50:  25nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074972(2,5-Bis-(3-cyclopentyloxy-4-methoxy-phenyl)-furan ...)
Affinity DataIC50:  44nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074965(4-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...)
Affinity DataIC50:  65nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074974(1-[2,5-Bis-(3,4-dimethoxy-phenyl)-furan-3-yl]-etha...)
Affinity DataIC50:  120nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074968(2-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...)
Affinity DataIC50:  190nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074977((2,5-Diphenyl-furan-3-yl)-phenyl-methanone | CHEMB...)
Affinity DataIC50:  340nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074969(3-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...)
Affinity DataIC50:  370nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074967(2,5-Bis-(3,4-dimethoxy-phenyl)-furan | CHEMBL11093...)
Affinity DataIC50:  560nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074975(CHEMBL325846 | [2-(3-Cyclopentyloxy-4-methoxy-phen...)
Affinity DataIC50:  590nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074973(2-[3-Benzenesulfonyl-5-(3-cyclopentyloxy-4-methoxy...)
Affinity DataIC50:  740nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074970(2-[4-Benzenesulfonyl-5-(3-cyclopentyloxy-4-methoxy...)
Affinity DataIC50:  770nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074966(4-(2,5-Diphenyl-furan-3-yl)-morpholine | CHEMBL323...)
Affinity DataIC50:  2.30E+3nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)
Affinity DataIC50:  4.00E+3nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074971(4-[(R)-2-(4-Cyclopentyloxy-3-methoxy-phenyl)-2-phe...)
Affinity DataIC50:  5.00E+3nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50074964(2,5-diphenylfuran | CHEMBL109224 | PPF)
Affinity DataIC50: >1.00E+4nMAssay Description:PDE4A activity assessed using human recombinant purified GST-PDE4A248More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed