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Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50034997
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50206060(1-(2,5-dimethoxyphenethyl)-3-(5-bromopyridin-2-yl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078263(1-(5-Bromo-pyridin-2-yl)-3-[2-(2-fluoro-phenyl)-et...)
Affinity DataIC50:  600nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078261(1-(5-Bromo-pyridin-2-yl)-3-[2-(2-chloro-phenyl)-et...)
Affinity DataIC50:  700nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078255(1-(5-Bromo-pyridin-2-yl)-3-[2-(3-fluoro-phenyl)-et...)
Affinity DataIC50:  700nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM2337(6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM1866(3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...)
Affinity DataIC50:  800nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM1944(BHAP deriv. | CHEMBL593 | DELAVIRDINE MESYLATE | D...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50081459(1-(5-Chloro-pyridin-2-yl)-3-(2-cyclohex-1-enyl-eth...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078253(4-Benzyl-3-isopropyl-6-methylsulfanylmethylsulfany...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078260(1-(5-Bromo-pyridin-2-yl)-3-piperidin-1-ylmethyl-th...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078254(1-(5-Bromo-pyridin-2-yl)-3-[2-(4-fluoro-phenyl)-et...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078262(4-(3,5-Dimethyl-benzyl)-3-isopropyl-6-methylsulfan...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078258(1-(5-Bromo-pyridin-2-yl)-3-morpholin-4-ylmethyl-th...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)