Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50009156
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080541BDBM50080541((2-Amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl)...)
Affinity DataEC50:  4.50E+3nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080546BDBM50080546((2-Amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl)...)
Affinity DataEC50:  4.70E+3nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080548BDBM50080548((2-Amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl)...)
Affinity DataEC50:  6.00E+3nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080547BDBM50080547((2-Amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl)...)
Affinity DataEC50:  6.20E+3nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080540BDBM50080540(CHEMBL57997 | CHEMBL203347 | (2-amino-4,5,6,7-tetr...)
Affinity DataEC50:  6.80E+3nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080544BDBM50080544((2-Amino-6-benzyl-4,5,6,7-tetrahydro-thieno[2,3-c]...)
Affinity DataEC50:  9.20E+3nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080543BDBM50080543((2-Amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl)...)
Affinity DataEC50:  1.05E+4nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080545BDBM50080545((2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]p...)
Affinity DataEC50:  1.13E+4nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080550BDBM50080550((2-amino-4,5-dimethylthien-3-yl)-[3-(trifluorometh...)
Affinity DataEC50:  1.47E+4nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080539BDBM50080539([2-Amino-6-(3-chloro-benzyl)-4,5,6,7-tetrahydro-th...)
Affinity DataEC50:  1.51E+4nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080551BDBM50080551((2-Amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl)...)
Affinity DataEC50:  1.64E+4nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080549BDBM50080549([2-Amino-6-(3,4-dichloro-benzyl)-4,5,6,7-tetrahydr...)
Affinity DataEC50:  3.20E+4nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080542BDBM50080542((2-Amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-yl)...)
Affinity DataEC50:  3.49E+4nMAssay Description:Enhanced 0.5 nM [3H]CCPA dissociation from adenosine A1 receptor of rat brain cortex membranes compared to 100 uM CPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed