TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 82nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 114nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 122nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 125nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 194nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 261nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 322nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 351nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 370nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 387nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 438nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 477nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 550nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 556nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 604nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 759nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 770nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 844nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 1.15E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 1.43E+3nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 1.53E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 1.77E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 5.85E+3nMAssay Description:Compound was tested for its affinity by the inhibition of [125I]RTI-55 binding at norepinephrine transporter (NET) transfected in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 5.90E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to serotonin transporter (SERT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 7.05E+3nMAssay Description:Inhibition of [125I]RTI-55 binding to norepinephrine transporter (NET) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 8.20E+3nMAssay Description:Inhibition of [125I]RTI-55 binding at Dopamine transporter (DAT) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of [3H]- 5-HT uptake in HEK cells expressing serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of [3H]- 5-HT uptake in HEK cells expressing serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of [3H]DA uptake in HEK cells expressing dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of [3H]- NE uptake in HEK cells expressing norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of [3H]DA uptake in HEK cells expressing dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of [3H]- NE uptake in HEK cells expressing norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of [3H]DA uptake in HEK cells expressing dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of [3H]DA uptake in HEK cells expressing dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of [3H]DA uptake in HEK cells expressing dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of [3H]DA uptake in HEK cells expressing dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of [3H]- NE uptake in HEK cells expressing norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:Inhibition of [3H]DA uptake in HEK cells expressing dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:Inhibition of [3H]- NE uptake in HEK cells expressing norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of [3H]DA uptake in HEK cells expressing dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 192nMAssay Description:Inhibition of [3H]- NE uptake in HEK cells expressing norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of [3H]- NE uptake in HEK cells expressing norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]- NE uptake in HEK cells expressing norepinephrine transporterMore data for this Ligand-Target Pair