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Report error Found 145 Enz. Inhib. hit(s) with all data for entry = 687
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5106(1,2,4-Oxadiazole Analogue 15c | 4-[(2S)-2-{[(1S)-2...)
Affinity DataIC50:  1.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5099(1,2,4-Oxadiazole Analogue 12c | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5105(1,2,4-Oxadiazole Analogue 15b | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5103(1,2,4-Oxadiazole Analogue 13c | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5090(1,2,4-Oxadiazole Analogue 14e | 4-[(2S)-2-[1-(naph...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5086(1,2,4-Oxadiazole Analogue 14a | 4-[(2S)-2-(1-pheny...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5074(1,2,4-Oxadiazole Analogue 5m | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5075(1,2,4-Oxadiazole Analogue 5n | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5104(1,2,4-Oxadiazole Analogue 15a | 4-[(2S)-2-{[(1S)-2...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5102(1,2,4-Oxadiazole Analogue 13b | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5100(1,2,4-Oxadiazole Analogue 12d | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5072(1,2,4-Oxadiazole Analogue 5k | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5098(1,2,4-Oxadiazole Analogue 12b | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5085(1,2,4-Oxadiazole Analogue 12g | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  4.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5096(1,2,4-Oxadiazole Analogue 5e | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5091(1,2,4-Oxadiazole Analogue 14f | 4-[(2S)-2-[1-(1H-i...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5073(1,2,4-Oxadiazole Analogue 5l | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5087(1,2,4-Oxadiazole Analogue 14b | 4-[(2S)-2-[1-(thio...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5071(1,2,4-Oxadiazole Analogue 5j | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5101(1,2,4-Oxadiazole Analogue 13a | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  5.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5088(1,2,4-Oxadiazole Analogue 14c | 4-[(2S)-2-[1-(3,4-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5089(1,2,4-Oxadiazole Analogue 14d | 4-[(2S)-2-[1-(4-me...)
Affinity DataIC50:  6.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5095(1,2,4-Oxadiazole Analogue 5d | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5084(1,2,4-Oxadiazole Analogue 12f | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5069(1,2,4-Oxadiazole Analogue 5i | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5097(1,2,4-Oxadiazole Analogue 5f | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  7.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5094(1,2,4-Oxadiazole Analogue 4j | 4-[(2S)-2-{[(1S)-3-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5082(1,2,4-Oxadiazole Analogue 12a | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  1.10E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5093(1,2,4-Oxadiazole Analogue 4f | 4-[(2S)-2-{[(1S)-3-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5066(1,2,4-Oxadiazole Analogue 5b | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5081(1,2,4-Oxadiazole Analogue 11 | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  1.40E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5071(1,2,4-Oxadiazole Analogue 5j | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  1.80E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5059(1,2,4-Oxadiazole Analogue 4d | 4-[(2S)-2-{[(1S)-3-...)
Affinity DataIC50:  2.60E+4nMpH: 7.4 T: 22°CAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5083(1,2,4-Oxadiazole Analogue 12e | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  3.10E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5069(1,2,4-Oxadiazole Analogue 5i | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  3.10E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5080(1,2,4-Oxadiazole Analogue 10 | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  3.20E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5084(1,2,4-Oxadiazole Analogue 12f | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  3.20E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5065(1,2,4-Oxadiazole Analogue 5a | 4-[(2S)-2-acetamido...)
Affinity DataIC50:  3.30E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5105(1,2,4-Oxadiazole Analogue 15b | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  3.50E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5058(1,2,4-Oxadiazole Analogue 4c | 4-[(2S)-2-{[(1S)-3-...)
Affinity DataIC50:  3.60E+4nMpH: 7.4 T: 22°CAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5085(1,2,4-Oxadiazole Analogue 12g | 4-[(2S)-2-acetamid...)
Affinity DataIC50:  3.70E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5072(1,2,4-Oxadiazole Analogue 5k | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  3.90E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5075(1,2,4-Oxadiazole Analogue 5n | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5079(1,2,4-Oxadiazole Analogue 9 | 4-[(2S)-2-{[(1S)-2-c...)
Affinity DataIC50:  4.30E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5073(1,2,4-Oxadiazole Analogue 5l | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  4.50E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5090(1,2,4-Oxadiazole Analogue 14e | 4-[(2S)-2-[1-(naph...)
Affinity DataIC50:  4.90E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5074(1,2,4-Oxadiazole Analogue 5m | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  5.00E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5063(1,2,4-Oxadiazole Analogue 4i | 4-[(2S)-2-{[(1S)-3-...)
Affinity DataIC50:  5.50E+4nMpH: 7.4 T: 22°CAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5103(1,2,4-Oxadiazole Analogue 13c | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  6.00E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5091(1,2,4-Oxadiazole Analogue 14f | 4-[(2S)-2-[1-(1H-i...)
Affinity DataIC50:  6.20E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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