Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50009327
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082309(CHEMBL101317 | N-(1H-Imidazol-2-ylmethyl)-guanidin...)
Affinity DataIC50:  1.38E+5nMAssay Description:Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082307((R)-2-Amino-5-[N'-(1H-imidazol-2-ylmethyl)-guanidi...)
Affinity DataIC50:  3.47E+5nMAssay Description:Inhibition of bovine endothelial nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082310((R)-2-Amino-5-{N'-[2-(1H-imidazol-2-yl)-ethyl]-gua...)
Affinity DataIC50:  6.29E+5nMAssay Description:Inhibition of bovine endothelial nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50078824(2-Phenyl-1H-imidazole | CHEMBL14189 | US9138393, 2...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082308((R)-2-Amino-5-{N'-[2-(3H-imidazol-4-yl)-ethyl]-gua...)
Affinity DataIC50:  1.09E+6nMAssay Description:Inhibition of bovine endothelial nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082310((R)-2-Amino-5-{N'-[2-(1H-imidazol-2-yl)-ethyl]-gua...)
Affinity DataIC50:  1.49E+6nMAssay Description:Inhibition of rat neuronal nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 uM L-a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Wake Forest University Winston-Salem

Curated by ChEMBL
LigandPNGBDBM50082307((R)-2-Amino-5-[N'-(1H-imidazol-2-ylmethyl)-guanidi...)
Affinity DataIC50:  1.59E+6nMAssay Description:Inhibition of rat neuronal nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 uM L-a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed