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Found 43 Enz. Inhib. hit(s) with all data for entry = 50009420
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083418(Biphenyl-2-yl-[1-(3H-imidazol-4-ylmethyl)-1,2,3,5-...)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083419(CHEMBL356840 | {1-[2-(1H-Imidazol-4-yl)-ethyl]-1,2...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083439(CHEMBL358680 | [1-(1H-Imidazol-4-ylmethyl)-1,2,3,5...)
Affinity DataIC50:  460nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083422(1-(3H-Imidazol-4-ylmethyl)-4-(naphthalene-1-sulfon...)
Affinity DataIC50:  480nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083433(CHEMBL151851 | {1-[3-(1H-Imidazol-2-yl)-propyl]-1,...)
Affinity DataIC50:  590nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083420((2-Benzylamino-phenyl)-[1-(3H-imidazol-4-ylmethyl)...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083405(1-[1-(3H-Imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-b...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083445(2-[1-(3H-Imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-b...)
Affinity DataIC50:  720nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083444(CHEMBL357974 | [1-(2-Aminomethyl-3H-imidazol-4-ylm...)
Affinity DataIC50:  840nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083438(CHEMBL424509 | [1-(3-Benzyl-3H-imidazol-4-ylmethyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083410(1-(3H-Imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benz...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083430(CHEMBL148816 | [(S)-4-(3H-Imidazol-4-ylmethyl)-3-(...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083428(CHEMBL348426 | {1-[2-(2-Amino-ethyl)-3H-imidazol-4...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083417(CHEMBL151813 | [4-(1H-Imidazol-4-ylmethyl)-2,3,4,5...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083412(CHEMBL151902 | [(S)-4-[2-(3H-Imidazol-4-yl)-ethyl]...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083435(CHEMBL348672 | [(S)-4-[3-(3H-Imidazol-4-yl)-propyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083409(CHEMBL355971 | [1-(3H-Imidazol-4-ylmethyl)-7-pyrid...)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083407(CHEMBL148487 | Cyclohexanecarboxylic acid [1-(3H-i...)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083425(CHEMBL342079 | [1-(1H-Imidazol-2-ylmethyl)-1,2,3,5...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083406(CHEMBL430778 | [1-(3H-Imidazol-4-ylmethyl)-7-pyrid...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083426(3-(3H-Imidazol-4-yl)-1-[(S)-2-(2-methoxy-ethyl)-4-...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083404(CHEMBL359140 | [1-(3H-Imidazol-4-ylmethyl)-4-(naph...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083415(CHEMBL358056 | N-[1-(3H-Imidazol-4-ylmethyl)-4-(na...)
Affinity DataIC50:  2.85E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083442(2-(3H-Imidazol-4-yl)-1-[(S)-2-(2-methoxy-ethyl)-4-...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083411(1-Cyclohexyl-3-[1-(3H-imidazol-4-ylmethyl)-4-(naph...)
Affinity DataIC50:  3.55E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083408(CHEMBL358499 | [1-(3H-Imidazol-4-ylmethyl)-7-pheny...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083414(1-[1-(3H-Imidazol-4-ylmethyl)-7-phenyl-1,2,3,5-tet...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083434(CHEMBL341861 | [1-(3H-Imidazol-4-ylmethyl)-7-pheny...)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083429(CHEMBL148870 | [2-(2-Hydroxy-ethylsulfanyl)-phenyl...)
Affinity DataIC50:  1.24E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083413(CHEMBL359092 | [1-(3H-Imidazol-4-ylmethyl)-7-pyrid...)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083427(CHEMBL149103 | N-[1-(3H-Imidazol-4-ylmethyl)-4-(na...)
Affinity DataIC50:  1.68E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083440(CHEMBL348237 | [1-(3H-Imidazol-4-ylmethyl)-7-pyrid...)
Affinity DataIC50:  1.77E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083436(CHEMBL348262 | [7-Cyclohexyl-1-(3H-imidazol-4-ylme...)
Affinity DataIC50:  1.86E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083423((3,4-Dihydro-2H-quinolin-1-yl)-[1-(3H-imidazol-4-y...)
Affinity DataIC50:  2.05E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083431(CHEMBL121010 | [7-Bromo-1-(3H-imidazol-4-ylmethyl)...)
Affinity DataIC50:  2.28E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083416(CHEMBL151633 | N-[1-(3H-Imidazol-4-ylmethyl)-4-(na...)
Affinity DataIC50:  2.49E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083441(CHEMBL151978 | [1-(3H-Imidazol-4-ylmethyl)-9-methy...)
Affinity DataIC50:  3.50E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083446(1-(3H-Imidazol-4-ylmethyl)-4-(naphthalene-1-sulfon...)
Affinity DataIC50:  4.26E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083421(CHEMBL150690 | [8-Chloro-1-(3H-imidazol-4-ylmethyl...)
Affinity DataIC50:  5.40E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083424(1-(3H-Imidazol-4-ylmethyl)-7-phenyl-4-(1-phenyl-1H...)
Affinity DataIC50:  7.02E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083437(CHEMBL150737 | [8-Amino-1-(3H-imidazol-4-ylmethyl)...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083443((4-Chloro-phenylamino)-[1-(3H-imidazol-4-ylmethyl)...)
Affinity DataIC50:  1.42E+6nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083432(1-(3H-Imidazol-4-ylmethyl)-4-naphthalen-1-ylmethyl...)
Affinity DataIC50:  2.97E+6nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed