Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50009476
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50053929(N-(9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]q...)
Affinity DataKi:  0.650nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 20 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50059376(L-249313 | 9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]tr...)
Affinity DataKi:  13nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 20 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50059375(5-Amino-3-(4-methoxy-phenyl)-thiazolo[3,2-a]pyrimi...)
Affinity DataKi:  18nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 20 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50084018(2-Phenylacetylamino-4,7-dihydro-5H-thieno[2,3-c]py...)
Affinity DataIC50: 186nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 20 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50084019(6,7-Dimethoxy-3-[4-(4-methoxy-phenyl)-thiazol-2-yl...)
Affinity DataIC50: 255nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 20 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50084017({[(2-Benzoylamino-5-bromo-phenyl)-phenyl-methyl]-a...)
Affinity DataIC50: 407nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 5 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenosi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50053924(CHEMBL89093 | MRS1067 | 3,6-Dichloro-2-(2-isopropo...)
Affinity DataKi:  560nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 20 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50084018(2-Phenylacetylamino-4,7-dihydro-5H-thieno[2,3-c]py...)
Affinity DataKi:  600nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 20 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50084019(6,7-Dimethoxy-3-[4-(4-methoxy-phenyl)-thiazol-2-yl...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of [35S]GTP-gamma-S, binding stimulated by 20 uM 5''-N-ethyluronamidoadenosine (NECA) in membranes of HEK293 cells expressing human Adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Chembridge

Curated by ChEMBL
LigandPNGBDBM50084017({[(2-Benzoylamino-5-bromo-phenyl)-phenyl-methyl]-a...)
Affinity DataKi:  3.10E+3nMAssay Description:In vitro binding affinity against human Adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed