Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 104 Enz. Inhib. hit(s) with all data for entry = 50041282
TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037463(2-(3-Methoxy-phenyl)-6-morpholin-4-yl-1H-quinolin-...)
Affinity DataIC50:  363nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037454(6-(3-Chloro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin...)
Affinity DataIC50:  372nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037448(6-Dimethylamino-2-(3-methoxy-phenyl)-1H-quinolin-4...)
Affinity DataIC50:  380nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037450(2-(3-Methoxy-phenyl)-6-pyrrolidin-1-yl-1H-quinolin...)
Affinity DataIC50:  437nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409014(CHEMBL50139)
Affinity DataIC50:  447nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50106309(2-(2'-fluorophenyl)-6-pyrolinyl-4-(1H)-quinolone |...)
Affinity DataIC50:  457nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037462(6-(3-Hydroxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinoli...)
Affinity DataIC50:  468nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037457(6-(3-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin...)
Affinity DataIC50:  525nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059968(2-(3-Fluoro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  525nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059964(6-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50:  550nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50056948(CHEMBL49847 | Isonicotinic acid (S)-1,2,3-trimetho...)
Affinity DataIC50:  562nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037444(6-(3-Methoxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinoli...)
Affinity DataIC50:  575nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409024(CHEMBL48525)
Affinity DataIC50:  617nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059971(2-(3-Fluoro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  631nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037459(6-(3-Methylamino-phenyl)-5H-[1,3]dioxolo[4,5-g]qui...)
Affinity DataIC50:  646nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50009568((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...)
Affinity DataIC50:  646nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059966(7-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50:  661nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50063845((S)-6-(3-Methoxy-phenyl)-6,7-dihydro-5H-[1,3]dioxo...)
Affinity DataIC50:  692nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037453(6-(3-Amino-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-...)
Affinity DataIC50:  724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409011(CHEMBL45711)
Affinity DataIC50:  724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059961(2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059975(2-(3-Fluoro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...)
Affinity DataIC50:  741nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50056949(CHEMBL49518 | Nicotinic acid (S)-1,2,3-trimethoxy-...)
Affinity DataIC50:  759nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059117(2-(3-Methoxy-phenyl)-7-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50:  759nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059978(5,7-Dimethyl-2-naphthalen-1-yl-1H-[1,8]naphthyridi...)
Affinity DataIC50:  776nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059976(2-(3-Chloro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...)
Affinity DataIC50:  776nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059111(2-(3-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50:  794nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037447(6-(3-Trifluoromethyl-phenyl)-5H-[1,3]dioxolo[4,5-g...)
Affinity DataIC50:  813nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059103(2-(3-Methoxy-phenyl)-5,7-dimethyl-1H-[1,8]naphthyr...)
Affinity DataIC50:  871nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059960(2-(3-Chloro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  891nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059972(5-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50:  933nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059122(2-(3-Methoxy-phenyl)-1H-[1,8]naphthyridin-4-one | ...)
Affinity DataIC50:  955nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409007(CHEMBL49419)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059969(2-Naphthalen-1-yl-1H-[1,8]naphthyridin-4-one | CHE...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014875((S)-7-Amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409001(CHEMBL299185)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409016(CHEMBL52480)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50056963(4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50041113(2-(3-Methoxy-phenyl)-1H-quinolin-4-one | CHEMBL276...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059959(2-(3-Chloro-phenyl)-1H-[1,8]naphthyridin-4-one | C...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409005(CHEMBL48701)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50064482(2-demethylthiocolchicine | CHEMBL277239 | N-((S)-2...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059977(6-Methyl-2-m-tolyl-1H-[1,8]naphthyridin-4-one | CH...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409017(CHEMBL48462)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081559(2-(5-Bromo-thiophen-2-yl)-7-methyl-1H-[1,8]naphthy...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409021(CHEMBL52534)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014853(CHEMBL277998 | N-((S)-3-Hydroxy-1,2-dimethoxy-10-m...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081576(2-(5-Chloro-thiophen-2-yl)-7-methyl-1H-[1,8]naphth...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409018(CHEMBL295520)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081560(7-Methyl-2-(5-methyl-thiophen-2-yl)-1H-[1,8]naphth...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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