Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50035078
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)
Affinity DataIC50:  0.470nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  0.720nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366659(CHEMBL1627354)
Affinity DataIC50:  3.5nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)
Affinity DataIC50:  6nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50169743((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366659(CHEMBL1627354)
Affinity DataIC50:  9nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366659(CHEMBL1627354)
Affinity DataIC50:  9nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366658(CHEMBL1628170)
Affinity DataIC50:  21nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366663(CHEMBL1627351)
Affinity DataIC50:  32nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366663(CHEMBL1627351)
Affinity DataIC50:  32nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366660(CHEMBL1628199)
Affinity DataIC50:  33nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366660(CHEMBL1628199)
Affinity DataIC50:  37nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50041611((2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRY...)
Affinity DataIC50:  39nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  43nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366658(CHEMBL1628170)
Affinity DataIC50:  46nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50041611((2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRY...)
Affinity DataIC50:  56nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366662(CHEMBL1627356)
Affinity DataIC50:  59nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366664(CHEMBL1627353)
Affinity DataIC50:  63nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366662(CHEMBL1627356)
Affinity DataIC50:  94nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366663(CHEMBL1627351)
Affinity DataIC50:  316nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366664(CHEMBL1627353)
Affinity DataIC50:  397nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366660(CHEMBL1628199)
Affinity DataIC50:  519nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50041611((2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRY...)
Affinity DataIC50:  654nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366664(CHEMBL1627353)
Affinity DataEC50:  7nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366657(CHEMBL1627361)
Affinity DataEC50:  336nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366662(CHEMBL1627356)
Affinity DataEC50:  173nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366661(CHEMBL1627355)
Affinity DataEC50:  5nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366660(CHEMBL1628199)
Affinity DataEC50:  28nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366663(CHEMBL1627351)
Affinity DataEC50:  40nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  0.00700nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366658(CHEMBL1628170)
Affinity DataEC50:  13nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed