Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50035103
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  9nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50366677(CHEMBL1794050)
Affinity DataIC50:  11nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085414(3-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(Z)-ylide...)
Affinity DataIC50:  13nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085408(2-Amino-8-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50:  16nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085412(5-Benzoyl-3-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth...)
Affinity DataIC50:  18nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085418(3-(3,5-dibromo-4-hydroxybenzylidene)-5-(cyclopropa...)
Affinity DataIC50:  25nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085417(3-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(Z)-ylide...)
Affinity DataIC50:  29nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085413(3-(3,5-dichloro-4-hydroxybenzylidene)-5-phenylindo...)
Affinity DataIC50:  32nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085411(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50:  40nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085411(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50:  46nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085416(5-(2-Chloro-acetyl)-3-[1-(3,5-dibromo-4-hydroxy-ph...)
Affinity DataIC50:  65nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085410(3-(3,5-dibromo-4-hydroxybenzylidene)indolin-2-one ...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed