Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50035103
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358043BDBM50358043(GW-5074 | CHEMBL1794051)
Affinity DataIC50: 9nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366677BDBM50366677(CHEMBL1794050)
Affinity DataIC50: 11nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085414BDBM50085414(3-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(Z)-ylide...)
Affinity DataIC50: 13nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085408BDBM50085408(2-Amino-8-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(...)
Affinity DataIC50: 16nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085412BDBM50085412(5-Benzoyl-3-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth...)
Affinity DataIC50: 18nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085418BDBM50085418(5-Cyclopropanecarbonyl-3-[1-(3,5-dibromo-4-hydroxy...)
Affinity DataIC50: 25nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085417BDBM50085417(3-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(Z)-ylide...)
Affinity DataIC50: 29nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085413BDBM50085413(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50: 32nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085411BDBM50085411(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50: 40nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085411BDBM50085411(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50: 46nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085416BDBM50085416(5-(2-Chloro-acetyl)-3-[1-(3,5-dibromo-4-hydroxy-ph...)
Affinity DataIC50: 65nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085410BDBM50085410(3-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(Z)-ylide...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed