Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50035107
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085518(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  10nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085511(CHEMBL103993 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  10nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085509(CHEMBL104995 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  12nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085523(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  12nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085519(CHEMBL102502 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  24nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085515(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  34nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085509(CHEMBL104995 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  52nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085518(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  57nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085519(CHEMBL102502 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085512(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  71nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085514(3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-...)
Affinity DataKi:  80nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085511(CHEMBL103993 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  80nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085521(CHEMBL553840 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  102nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085523(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  120nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085515(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  130nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085514(3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-...)
Affinity DataKi:  170nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085512(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  190nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085522(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  200nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085516(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  200nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085517(CHEMBL556200 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  220nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085521(CHEMBL553840 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  282nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085511(CHEMBL103993 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085518(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085510(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  670nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085520(CHEMBL432783 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  800nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085524(CHEMBL102578 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  900nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085517(CHEMBL556200 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085514(3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085509(CHEMBL104995 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085519(CHEMBL102502 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085521(CHEMBL553840 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085522(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085515(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085523(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085517(CHEMBL556200 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085510(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085512(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  6.30E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085516(Cyclic urea 2,4-diazepin-3-one analogue | bis(2,2,...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085513(CHEMBL101586 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085524(CHEMBL102578 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi:  1.18E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085513(CHEMBL101586 | Cyclic urea 2,4-diazepin-3-one anal...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed