Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50035107
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085511BDBM50085511(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  10nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085518BDBM50085518(bis(2,2,2-trifluoroacetate); {amino[3-(2-oxo-3-{1-...)
Affinity DataKi:  10nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085523BDBM50085523(bis(2,2,2-trifluoroacetate); [amino(3-{2-oxo-3-[1-...)
Affinity DataKi:  12nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085509BDBM50085509(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  12nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085519BDBM50085519(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  24nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085515BDBM50085515(bis(2,2,2-trifluoroacetate); {amino[3-(3-{1-[(2-am...)
Affinity DataKi:  34nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085509BDBM50085509(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  52nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085518BDBM50085518(bis(2,2,2-trifluoroacetate); {amino[3-(2-oxo-3-{1-...)
Affinity DataKi:  57nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085519BDBM50085519(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085512BDBM50085512(bis(2,2,2-trifluoroacetate); {amino[3-(3-{1-[(4-am...)
Affinity DataKi:  71nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085511BDBM50085511(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  80nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085514BDBM50085514(3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-...)
Affinity DataKi:  80nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085521BDBM50085521(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL55...)
Affinity DataKi:  102nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085523BDBM50085523(bis(2,2,2-trifluoroacetate); [amino(3-{2-oxo-3-[1-...)
Affinity DataKi:  120nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085515BDBM50085515(bis(2,2,2-trifluoroacetate); {amino[3-(3-{1-[(2-am...)
Affinity DataKi:  130nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085514BDBM50085514(3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-...)
Affinity DataKi:  170nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085512BDBM50085512(bis(2,2,2-trifluoroacetate); {amino[3-(3-{1-[(4-am...)
Affinity DataKi:  190nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085516BDBM50085516(bis(2,2,2-trifluoroacetate); [amino(3-{2-oxo-3-[1-...)
Affinity DataKi:  200nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085522BDBM50085522(bis(2,2,2-trifluoroacetate); {amino[3-(3-{1-[(3-am...)
Affinity DataKi:  200nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085517BDBM50085517(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL55...)
Affinity DataKi:  220nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085521BDBM50085521(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL55...)
Affinity DataKi:  282nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085511BDBM50085511(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085518BDBM50085518(bis(2,2,2-trifluoroacetate); {amino[3-(2-oxo-3-{1-...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085510BDBM50085510(bis(2,2,2-trifluoroacetate); [amino(3-{2-oxo-3-[1-...)
Affinity DataKi:  670nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085520BDBM50085520(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL43...)
Affinity DataKi:  800nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085524BDBM50085524(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  900nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085517BDBM50085517(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL55...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085514BDBM50085514(3-[2-Oxo-3-(1-thiophen-2-ylmethyl-piperidin-4-yl)-...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085509BDBM50085509(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085519BDBM50085519(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085521BDBM50085521(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL55...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085522BDBM50085522(bis(2,2,2-trifluoroacetate); {amino[3-(3-{1-[(3-am...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085515BDBM50085515(bis(2,2,2-trifluoroacetate); {amino[3-(3-{1-[(2-am...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085523BDBM50085523(bis(2,2,2-trifluoroacetate); [amino(3-{2-oxo-3-[1-...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085517BDBM50085517(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL55...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085510BDBM50085510(bis(2,2,2-trifluoroacetate); [amino(3-{2-oxo-3-[1-...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085512BDBM50085512(bis(2,2,2-trifluoroacetate); {amino[3-(3-{1-[(4-am...)
Affinity DataKi:  6.30E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085516BDBM50085516(bis(2,2,2-trifluoroacetate); [amino(3-{2-oxo-3-[1-...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085513BDBM50085513(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085524BDBM50085524(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  1.18E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085513BDBM50085513(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed