Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50009651
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086083BDBM50086083(1-[2-(3,4,5-Trimethoxy-phenyl)-pent-4-enoyl]-piper...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086090BDBM50086090(1-[2-(3,4,5-Trimethoxy-phenyl)-butyryl]-piperidine...)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086094BDBM50086094(1-[2-(3,4,5-Trimethoxy-phenyl)-pentanoyl]-piperidi...)
Affinity DataIC50: 3.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086077BDBM50086077(1-[3-Cyclopropyl-2-(3,4,5-trimethoxy-phenyl)-propi...)
Affinity DataIC50: 4.40nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086092BDBM50086092(1-[3-Methyl-2-(3,4,5-trimethoxy-phenyl)-butyryl]-p...)
Affinity DataIC50: 5.80nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086078BDBM50086078(1-(2-Cyclohexyl-2-phenyl-acetyl)-piperidine-2-carb...)
Affinity DataIC50: 12nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086087BDBM50086087(1-(3-Methyl-2-phenyl-butyryl)-piperidine-2-carboxy...)
Affinity DataIC50: 19nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086082BDBM50086082(1-[2-(3,4,5-Trimethoxy-phenyl)-pent-4-enoyl]-piper...)
Affinity DataIC50: 19nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086085BDBM50086085(1-(2-Phenyl-butyryl)-piperidine-2-carboxylic acid ...)
Affinity DataIC50: 40nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086075BDBM50086075(1-[2-(3,4,5-Trimethoxy-phenyl)-pentanoyl]-piperidi...)
Affinity DataIC50: 43nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086086BDBM50086086(1-[3-Methyl-2-(3,4,5-trimethoxy-phenyl)-butyryl]-p...)
Affinity DataIC50: 65nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086079BDBM50086079(1-(2-Cyclohexyl-2-phenyl-acetyl)-piperidine-2-carb...)
Affinity DataIC50: 66nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086080BDBM50086080(1-(2-Phenyl-propionyl)-piperidine-2-carboxylic aci...)
Affinity DataIC50: 94nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086089BDBM50086089(1-[3-Cyclopropyl-2-(3,4,5-trimethoxy-phenyl)-propi...)
Affinity DataIC50: 126nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086084BDBM50086084(1-(2-Phenyl-butyryl)-piperidine-2-carboxylic acid ...)
Affinity DataIC50: 133nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086081BDBM50086081(1-(3-Methyl-2-phenyl-butyryl)-piperidine-2-carboxy...)
Affinity DataIC50: 150nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086093BDBM50086093(1-[2-(3,4,5-Trimethoxy-phenyl)-butyryl]-piperidine...)
Affinity DataIC50: 187nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086076BDBM50086076(1-Diphenylacetyl-piperidine-2-carboxylic acid 1-(3...)
Affinity DataIC50: 273nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086091BDBM50086091(1-(2-Phenyl-propionyl)-piperidine-2-carboxylic aci...)
Affinity DataIC50: 590nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Ariad Gene Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132547BDBM50132547(1-Phenylacetyl-piperidine-2-carboxylic acid 1-(3-c...)
Affinity DataIC50: 1.53E+3nMAssay Description:Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed