Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50042162
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85122BDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 79.4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81346BDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 79.4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421427BDBM50421427(CHEMBL543228)
Affinity DataIC50: 501nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421417BDBM50421417(CHEMBL541346)
Affinity DataIC50: 630nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421425BDBM50421425(CHEMBL544872)
Affinity DataIC50: 794nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421423BDBM50421423(CHEMBL543939)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81346BDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421426BDBM50421426(CHEMBL552585)
Affinity DataIC50: 3.16E+3nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85122BDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81346BDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85122BDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81346BDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85122BDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421422BDBM50421422(CHEMBL543226)
Affinity DataIC50: 1.26E+4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4313BDBM4313(CHEMBL56543 | (2E)-N-benzyl-2-cyano-3-(3,4-dihydro...)
Affinity DataIC50: 1.26E+4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421420BDBM50421420(CHEMBL225385)
Affinity DataIC50: 1.26E+4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421418BDBM50421418(CHEMBL542522)
Affinity DataIC50: 1.58E+4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85122BDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Janus kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81346BDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of Janus kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421424BDBM50421424(CHEMBL542762)
Affinity DataIC50: 2.00E+5nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421421BDBM50421421(CHEMBL154693)
Affinity DataIC50: 5.01E+5nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218575BDBM50218575(CHEMBL544174)
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218574BDBM50218574(CHEMBL540593)
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218573BDBM50218573(CHEMBL542023)
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218571BDBM50218571(CHEMBL541100)
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218572BDBM50218572(CHEMBL154877)
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed