Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 1208
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10024(5-(1H-imidazol-1-ylmethyl)-5,6,7,8-tetrahydroquino...)
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10025(CHEMBL53068 | 5-(1H-imidazol-1-ylmethyl)-7,8-dihyd...)
Affinity DataIC50: 170nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10031(CHEMBL53290 | 5-[3-(Imidazol-1-yl)propyl]-7,8-dihy...)
Affinity DataIC50: 220nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10027(5-[2-(Imidazol-1-yl)ethyl]-7,8-dihydroquinoline | ...)
Affinity DataIC50: 290nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10030(5-[3-(1H-imidazol-1-yl)propyl]-5,6,7,8-tetrahydroq...)
Affinity DataIC50: 350nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10028(5-[2-(Imidazol-1-yl)ethyl]quinoline | CHEMBL54803 ...)
Affinity DataIC50: 350nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10026(5-[2-(Imidazol-1-yl)ethyl]-5,6,7,8-tetrahydroquino...)
Affinity DataIC50: 380nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10033(1-[2-(4,5,6,7-tetrahydro-1-benzothiophen-4-yl)ethy...)
Affinity DataIC50: 440nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10027(5-[2-(Imidazol-1-yl)ethyl]-7,8-dihydroquinoline | ...)
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10026(5-[2-(Imidazol-1-yl)ethyl]-5,6,7,8-tetrahydroquino...)
Affinity DataIC50: 630nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10031(CHEMBL53290 | 5-[3-(Imidazol-1-yl)propyl]-7,8-dihy...)
Affinity DataIC50: 680nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10036(1-[(2E)-2-(6,7-dihydro-1-benzothien-4(5H)-ylidene)...)
Affinity DataIC50: 680nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10029(1-[2-(1,2,3,4-tetrahydronaphthalen-1-yl)ethyl]-1H-...)
Affinity DataIC50: 700nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10032(1-[2-(4,5,6,7-Tetrahydrobenzo[b]furan-4-yl)ethyl]-...)
Affinity DataIC50: 920nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10032(1-[2-(4,5,6,7-Tetrahydrobenzo[b]furan-4-yl)ethyl]-...)
Affinity DataIC50: 1.01E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 1.10E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10028(5-[2-(Imidazol-1-yl)ethyl]quinoline | CHEMBL54803 ...)
Affinity DataIC50: 1.20E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10033(1-[2-(4,5,6,7-tetrahydro-1-benzothiophen-4-yl)ethy...)
Affinity DataIC50: 1.23E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10037(1-[(2Z)-2-(6,7-dihydro-1-benzothien-4(5H)-ylidene)...)
Affinity DataIC50: 1.26E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10041(7-[(Imidazol-1-yl)methyl]isoquinoline | CHEMBL2987...)
Affinity DataIC50: 1.38E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10025(CHEMBL53068 | 5-(1H-imidazol-1-ylmethyl)-7,8-dihyd...)
Affinity DataIC50: 1.50E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10036(1-[(2E)-2-(6,7-dihydro-1-benzothien-4(5H)-ylidene)...)
Affinity DataIC50: 1.70E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10024(5-(1H-imidazol-1-ylmethyl)-5,6,7,8-tetrahydroquino...)
Affinity DataIC50: 2.00E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10030(5-[3-(1H-imidazol-1-yl)propyl]-5,6,7,8-tetrahydroq...)
Affinity DataIC50: 2.30E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10034(1-{2-[(4E)-4,5,6,7-tetrahydro-1-benzofuran-4-ylide...)
Affinity DataIC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10040(6-(1H-imidazol-1-yl)isoquinoline | CHEMBL299066 | ...)
Affinity DataIC50: 3.06E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10029(1-[2-(1,2,3,4-tetrahydronaphthalen-1-yl)ethyl]-1H-...)
Affinity DataIC50: 3.40E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10034(1-{2-[(4E)-4,5,6,7-tetrahydro-1-benzofuran-4-ylide...)
Affinity DataIC50: 3.55E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10038(1-[2-(1-benzothiophen-4-yl)ethyl]-1H-imidazole | 1...)
Affinity DataIC50: 3.56E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10037(1-[(2Z)-2-(6,7-dihydro-1-benzothien-4(5H)-ylidene)...)
Affinity DataIC50: 3.90E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10035(CHEMBL56059 | 1-{2-[(4Z)-4,5,6,7-tetrahydro-1-benz...)
Affinity DataIC50: 4.10E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10038(1-[2-(1-benzothiophen-4-yl)ethyl]-1H-imidazole | 1...)
Affinity DataIC50: 5.30E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10041(7-[(Imidazol-1-yl)methyl]isoquinoline | CHEMBL2987...)
Affinity DataIC50: 5.40E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10035(CHEMBL56059 | 1-{2-[(4Z)-4,5,6,7-tetrahydro-1-benz...)
Affinity DataIC50: 6.00E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10023(5-(Imidazol-1-yl)-5,6,7,8-tetrahydroquinoline | 5-...)
Affinity DataIC50: 6.40E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 1.85E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10039(8-(1H-imidazol-1-yl)-5,6,7,8-tetrahydroquinoline |...)
Affinity DataIC50: 1.11E+5nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10023(5-(Imidazol-1-yl)-5,6,7,8-tetrahydroquinoline | 5-...)
Affinity DataAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10039(8-(1H-imidazol-1-yl)-5,6,7,8-tetrahydroquinoline |...)
Affinity DataAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Universitat Des Saarlandes

LigandPNGBDBM10040(6-(1H-imidazol-1-yl)isoquinoline | CHEMBL299066 | ...)
Affinity DataAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed