Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50009838
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088465(1-Phenyl-3-(3-pyridin-2-yl-isoquinolin-1-yl)-urea ...)
Affinity DataKi:  76nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067082((2-Amino-ethyl)-carbamic acid 4-(2,6-dioxo-1,3-dip...)
Affinity DataKi:  108nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067081(9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[...)
Affinity DataKi:  143nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088466(9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]triazolo[5,1-...)
Affinity DataKi:  172nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067096(CHEMBL71053 | N-(3-(pyridin-2-yl)isoquinolin-1-yl)...)
Affinity DataKi:  200nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067079(1-Phenyl-2-(3-pyridin-2-yl-isoquinolin-1-yl)-ethan...)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]-DPCPX from adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067079(1-Phenyl-2-(3-pyridin-2-yl-isoquinolin-1-yl)-ethan...)
Affinity DataKi:  660nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067089(CHEMBL72897 | N-(3-Pyridin-2-yl-isoquinolin-1-yl)-...)
Affinity DataKi:  730nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067096(CHEMBL71053 | N-(3-(pyridin-2-yl)isoquinolin-1-yl)...)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]-DPCPX from adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088475(1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-quinazolin-...)
Affinity DataKi:  4.03E+3nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088478(1-(2-Pyridin-3-yl-quinazolin-4-yl)-3-o-tolyl-urea ...)
Affinity DataKi:  2.39E+4nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088463(1-(2-Methoxy-phenyl)-3-(2-pyridin-2-yl-quinazolin-...)
Affinity DataKi:  2.82E+4nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088462(1-Phenyl-3-(2-pyridin-3-yl-quinazolin-4-yl)-urea |...)
Affinity DataKi:  5.09E+4nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088469(1-(2-(diethylamino)quinazolin-4-yl)-3-phenylurea |...)
Affinity DataKi:  6.48E+4nMAssay Description:Displacement of [3H]-DPCPX from adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088473(1-Phenyl-3-(2-pyrrolidin-1-yl-quinazolin-4-yl)-ure...)
Affinity DataKi:  8.23E+4nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088463(1-(2-Methoxy-phenyl)-3-(2-pyridin-2-yl-quinazolin-...)
Affinity DataKi:  8.45E+4nMAssay Description:Displacement of [3H]-DPCPX from adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088471(1-(2-Methoxy-phenyl)-3-(2-phenyl-quinazolin-4-yl)-...)
Affinity DataKi:  8.73E+4nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088477(1-(2-Phenyl-quinazolin-4-yl)-3-o-tolyl-urea | CHEM...)
Affinity DataKi:  1.15E+5nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088470(1-Phenyl-3-(2-pyridin-4-yl-quinazolin-4-yl)-urea |...)
Affinity DataKi:  1.66E+5nMAssay Description:Displacement of [3H]-DPCPX from adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088462(1-Phenyl-3-(2-pyridin-3-yl-quinazolin-4-yl)-urea |...)
Affinity DataKi:  1.70E+5nMAssay Description:Displacement of [3H]-DPCPX from adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088469(1-(2-(diethylamino)quinazolin-4-yl)-3-phenylurea |...)
Affinity DataKi:  1.78E+5nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088460(1-(2-Chloro-phenyl)-3-(2-phenyl-quinazolin-4-yl)-u...)
Affinity DataKi:  2.20E+5nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088468(1-(2-Furan-2-yl-quinazolin-4-yl)-3-phenyl-urea | C...)
Affinity DataKi:  2.57E+5nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088474(1-[2-(6-Methyl-pyridin-2-yl)-quinazolin-4-yl]-3-ph...)
Affinity DataKi:  2.64E+5nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088467(1-Phenyl-3-(2-phenyl-quinazolin-4-yl)-urea | CHEMB...)
Affinity DataKi:  2.87E+5nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088478(1-(2-Pyridin-3-yl-quinazolin-4-yl)-3-o-tolyl-urea ...)
Affinity DataKi:  2.95E+5nMAssay Description:Displacement of [3H]-DPCPX from adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088470(1-Phenyl-3-(2-pyridin-4-yl-quinazolin-4-yl)-urea |...)
Affinity DataKi:  3.36E+5nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088476(1-Phenyl-3-(2-pyridin-2-yl-quinazolin-4-yl)-urea |...)
Affinity DataKi:  4.95E+5nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088472(1-Phenyl-3-quinazolin-4-yl-urea | 1-phenyl-3-(quin...)
Affinity DataKi:  1.18E+6nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088459(1-[2-(4,6-Dimethyl-pyrimidin-2-yl)-quinazolin-4-yl...)
Affinity DataKi:  1.26E+6nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088461(1-(3-Methoxy-phenyl)-3-(2-phenyl-quinazolin-4-yl)-...)
Affinity DataKi:  2.04E+6nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088471(1-(2-Methoxy-phenyl)-3-(2-phenyl-quinazolin-4-yl)-...)
Affinity DataKi:  3.87E+6nMAssay Description:Displacement of [3H]-DPCPX from adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088464(1-(2-tert-Butyl-quinazolin-4-yl)-3-phenyl-urea | C...)
Affinity DataKi:  7.87E+7nMAssay Description:Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed