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Found 25 Enz. Inhib. hit(s) with all data for entry = 50009888
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50085867(2-(4-((S)-3-(1-((S)-4-amino-1-(3-(naphthalen-1-yl)...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50085872(2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50085877(CHEMBL355066 | N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-n...)
Affinity DataIC50:  600nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50050962(2-{4-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamin...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50085866(2-{4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50072868(5-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088879(CHEMBL168417 | {4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088893((S)-4-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-carboxy-p...)
Affinity DataIC50:  3.20E+3nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50050961(2-{4-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamin...)
Affinity DataIC50:  1.00E+4nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50085871(CHEMBL174418 | N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-n...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088881(5-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3...)
Affinity DataIC50:  1.90E+4nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088883(4-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088887(5-[(S)-2-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088889(CHEMBL355764 | N-((S)-2-(3,4-Bis-carboxymethoxy-ph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088885(2-{4-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamin...)
Affinity DataIC50:  4.30E+5nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088877((S)-4-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-carboxy-p...)
Affinity DataIC50:  6.50E+5nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088890((S)-4-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-carboxy-p...)
Affinity DataIC50:  8.00E+5nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088878((S)-4-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-carboxy-p...)
Affinity DataIC50:  1.20E+6nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088888(2-{4-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamin...)
Affinity DataIC50:  1.50E+6nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088882((S)-4-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-carboxy-p...)
Affinity DataIC50:  2.50E+6nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088892(5-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3...)
Affinity DataIC50:  3.70E+6nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088886(4-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3...)
Affinity DataIC50:  4.40E+6nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088884(5-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3...)
Affinity DataIC50:  4.60E+6nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088880(4-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3...)
Affinity DataIC50:  5.30E+6nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50088891((S)-4-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-carboxy-p...)
Affinity DataIC50:  1.30E+7nMAssay Description:Tested for binding affinity of the compound towards Protein-tyrosine Phospatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed