Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50010024
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090113((S)-2-(2-Hydroxy-5-nitro-benzylamino)-N-(3-methyl-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090117((S)-2-(2-Hydroxy-5-nitro-benzylamino)-3-phenyl-pro...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090108((S)-2-(2-Hydroxy-5-nitro-benzylamino)-3-phenyl-pro...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090119((S)-2-(2-Hydroxy-5-nitro-benzylamino)-3-phenyl-pro...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090105((S)-2-(2-Hydroxy-5-nitro-benzylamino)-3-phenyl-pro...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090116((S)-2-(2-Methoxy-benzylamino)-3-phenyl-propionic a...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090115((S)-2-(3-Hydroxy-benzylamino)-3-phenyl-propionic a...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090107((S)-2-(2-Hydroxy-benzylamino)-3-phenyl-propionic a...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090118((S)-2-(2-Hydroxy-5-nitro-benzylamino)-3-phenyl-pro...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090110((S)-2-(4-Hydroxy-benzylamino)-3-phenyl-propionic a...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090111((S)-2-Benzylamino-3-phenyl-propionic acid tert-but...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090106((S)-2-(2-Fluoro-benzylamino)-3-phenyl-propionic ac...)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090109((S)-2-(4-Fluoro-benzylamino)-3-phenyl-propionic ac...)
Affinity DataIC50: 1.21E+5nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090120((S)-2-(3-Methoxy-benzylamino)-3-phenyl-propionic a...)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090114((S)-2-(4-Methoxy-benzylamino)-3-phenyl-propionic a...)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Millennium Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50090112((S)-2-(3-Fluoro-benzylamino)-3-phenyl-propionic ac...)
Affinity DataIC50: 1.76E+5nMAssay Description:Inhibition of alpha-4 beta7/MAdCAM mediated cell adhesion was evaluated using B-cell lymphoma RPMI 8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed